Synonyms: ZLN 005 | ZLN-005
Compound class:
Synthetic organic
Comment: ZLN005 acts as a transcriptional activator of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α; PPARGC1A) [6]. Activation of the AMP-activated protein kinase pathway is implicated in the induction of PGC-1α expression. ZLN005 appears to produce cytoprotective/neuroprotective actions by enhancing mitochondrial fatty acid oxidation, respiration and biogenesis in a range of cell types and pathologies [1,3-5,7], and attenuating oxidative stress and necroptosis.
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Classification ![]() |
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Compound class | Synthetic organic |
IUPAC Name ![]() |
2-(4-tert-butylphenyl)-1H-benzimidazole |
Synonyms ![]() |
ZLN 005 | ZLN-005 |
Database Links ![]() |
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ChEMBL Ligand | CHEMBL4303368 |
GtoPdb PubChem SID | 491300037 |
PubChem CID | 899323 |
Search Google for chemical match using the InChIKey | LQUNNCQSFFKSSK-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | LQUNNCQSFFKSSK |
UniChem Compound Search for chemical match using the InChIKey | LQUNNCQSFFKSSK-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | LQUNNCQSFFKSSK-UHFFFAOYSA-N |
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ZLN005 (links to external site)
Cat. No. HY-17538 |