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thrombospondin 1   Click here for help

GtoPdb Ligand ID: 13047

Synonyms: THBS-1 | TSP-1 | TSP1
Immunopharmacology Ligand
Compound class: Endogenous peptide in human, mouse or rat
Comment: Thrombospondin 1 is glycoprotein that is involved in cell-to-cell and cell-to-matrix interactions. It is a ligand for cell surface receptors including CD47 [2-3], CD36 [1,4-5] and SIRPα [6]. Thrombospondin 1's receptor interactions are invloved in multiple biological processes, including inflammation, angiogenesis, wound healing, apoptosis, stem cell self-renewal, cardiovascular, metabolic and immune homeostasis, and resolution of inflammation.
Species: Human
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Synonyms Click here for help
THBS-1 | TSP-1 | TSP1
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
THBS1 thrombospondin 1 Human thrombospondin-1 precursor -
Database Links Click here for help
Ensembl Gene ENSG00000137801 (Hs)
Entrez Gene 7057 (Hs)
GtoPdb PubChem SID 491299829
Human Protein Atlas ENSG00000137801 (Hs)
UniProtKB P07996 (Hs)