Synonyms: cephamandole
cefamandole is an approved drug (FDA (1978))
Compound class:
Synthetic organic
Comment: Cefamandole is a semisynthetic, second generation cephalosporin belonging to the β-lactam class of antibacterial compounds [1]. It has broad-spectrum activity and is β-lactamase-resistant. It is administered parenterally as the prodrug cefamandole nafate.
Because of its inhibitory activity towards human aldehyde dehydrogenase, cefamandole produces an effect to ethanol similar to that produced by disulfiram (Antabuse®). |
|
Bioactivity Comments |
Cefamandole has broad-spectrum antibacterial activity [1]. |