Synonyms: CaCP-29 | Gohibic® | IFX-1
vilobelimab is an approved drug
Compound class:
Antibody
Comment: Vilobelimab (IFX-1) is a chimeric IgG4 monoclonal antibody against the terminal complement component, anaphylatoxin C5a. It was developed for potential to treat complement mediated inflammatory diseases. Vilobelimab blocks C5a/C5aR1 signalling in subsets of myeloid-derived suppressor cells (MDSCs) and neutrophils.
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Classification ![]() |
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Compound class | Antibody |
Approved drug? | Yes. EMA (2025) |
International Nonproprietary Names ![]() |
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INN number | INN |
11304 | vilobelimab |
Synonyms ![]() |
CaCP-29 | Gohibic® | IFX-1 |
Database Links ![]() |
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Specialist databases | |
IMGT/mAb-DB | 1038 |
Other databases | |
GtoPdb PubChem SID | 440816715 |
Search PubMed clinical trials | vilobelimab |
Search PubMed titles | vilobelimab |
Search PubMed titles/abstracts | vilobelimab |