BNC375

Ligand id: 10693

Name: BNC375

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 89.8
Molecular weight 394.11
XLogP 3.9
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
4-[(1R,3R)-3-[(5-chloro-2-methoxyanilino)methyl]-2,2-dimethylcyclopropyl]benzenesulfonamide
Synonyms
CS-0095916 | HY-128575
Comments
BNC375 is a potent, selective, and orally available type I positive allosteric modulator of α7 nicotinic acetylcholine receptor (nAChR).
Database Links
CAS Registry No. 1557240-80-8
GtoPdb PubChem SID 404859140
PubChem CID 118160666
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