IMB-808

Ligand id: 10034

Name: IMB-808

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 67.87
Molecular weight 380.1
XLogP 2.14
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-methyl-N-[2-oxo-2-[(2,3,4-trifluorophenyl)amino]ethyl]-2,3-dihydro-1,4-benzodioxine-7-carboxamide
Comments
IMB-808 is a liver X receptor partial agonist that shows anti-atherosclerotic potential [1-2]. It exhibits dual LXRα/β agonism but is devoid of the common lipogenic side effects of LXR full agonists [2].
Database Links
ChEMBL Ligand CHEMBL1316881
GtoPdb PubChem SID 375973222
PubChem CID 8001903
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