compound 29 [Moslin et al., 2017] [Ligand Id: 9992] activity data from GtoPdb

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  • phosphodiesterase 4D in Human [GtoPdb: 1303] [UniProtKB: Q08499]
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  • tyrosine kinase 2 in Human [GtoPdb: 2269] [UniProtKB: P29597]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
phosphodiesterase 4D in Human [GtoPdb: 1303] [UniProtKB: Q08499]
GtoPdb Binding affinity calculated be measuring displacement of [3H]cAMP binding to purified recombinant His-Tb-hPDE4D2. - 7.37 pIC50 43 nM IC50 Medchemcomm (2017) 8: 700-712 [PMID:30108788]
tyrosine kinase 2 in Human [GtoPdb: 2269] [UniProtKB: P29597]
GtoPdb Measuring binding to the JH2 pseudokinase domain of human TYK2. - 8.4 pIC50 4 nM IC50 Medchemcomm (2017) 8: 700-712 [PMID:30108788]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.