compound 29 [Moslin et al., 2017] [Ligand Id: 9992] activity data from GtoPdb

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

  • phosphodiesterase 4D in Human [GtoPdb: 1303] [UniProtKB: Q08499]
Created with Highcharts 10.3.3ValuesChart context menuphosphodiesterase 4DpKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • tyrosine kinase 2 in Human [GtoPdb: 2269] [UniProtKB: P29597]
Created with Highcharts 10.3.3ValuesChart context menutyrosine kinase 2pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
phosphodiesterase 4D in Human [GtoPdb: 1303] [UniProtKB: Q08499]
GtoPdb Binding affinity calculated be measuring displacement of [3H]cAMP binding to purified recombinant His-Tb-hPDE4D2. - 7.37 pIC50 43 nM IC50 Medchemcomm (2017) 8: 700-712 [PMID:30108788]
tyrosine kinase 2 in Human [GtoPdb: 2269] [UniProtKB: P29597]
GtoPdb Measuring binding to the JH2 pseudokinase domain of human TYK2. - 8.4 pIC50 4 nM IC50 Medchemcomm (2017) 8: 700-712 [PMID:30108788]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.