MK-8353 [Ligand Id: 9974] activity data from GtoPdb

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

  • mitogen-activated protein kinase 3 in Human [GtoPdb: 1494] [UniProtKB: P27361]
  • This target only has 0 pki data point
  • 0
1 _lig_chart_1 mitogen-activated protein kinase 3 Human
There should be some charts here, you may need to enable JavaScript!
  • mitogen-activated protein kinase 1 in Human [GtoPdb: 1495] [UniProtKB: P28482]
  • This target only has 0 pki data point
  • 0
2 _lig_chart_2 mitogen-activated protein kinase 1 Human
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
mitogen-activated protein kinase 3 in Human [GtoPdb: 1494] [UniProtKB: P27361]
GtoPdb Measuring inhibition of activated ERK1 in a IMAP kinase assay. - 7.64 pIC50 23 nM IC50 JCI Insight (2018) 3: null [PMID:29467321]
mitogen-activated protein kinase 1 in Human [GtoPdb: 1495] [UniProtKB: P28482]
GtoPdb Measuring inhibition of activated ERK2 in a IMAP kinase assay. - 8.06 pIC50 8.8 nM IC50 JCI Insight (2018) 3: null [PMID:29467321]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.