compound 7c [PMID: 22041175] [Ligand Id: 9931] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1962788 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| NADPH oxidase 1 in Human [GtoPdb: 3001] [UniProtKB: Q9Y5S8] | ||||||||
| GtoPdb | - | - | 7 | pKi | 101 | nM | Ki | Bioorg Med Chem (2011) 19: 6989-99 [PMID:22041175] |
| cytochrome b-245 beta chain in Human [GtoPdb: 3002] [UniProtKB: P04839] | ||||||||
| GtoPdb | - | - | 5.87 | pKi | 1340 | nM | Ki | Bioorg Med Chem (2011) 19: 6989-99 [PMID:22041175] |
| NADPH oxidase 4 in Human [GtoPdb: 3004] [UniProtKB: Q9NPH5] | ||||||||
| GtoPdb | - | - | 7.14 | pKi | 72 | nM | Ki | Bioorg Med Chem (2011) 19: 6989-99 [PMID:22041175] |
| NADPH oxidase 5 in Human [GtoPdb: 3005] [UniProtKB: Q96PH1] | ||||||||
| GtoPdb | - | - | 6.38 | pKi | 414 | nM | Ki | Bioorg Med Chem (2011) 19: 6989-99 [PMID:22041175] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
