compound 7c [PMID: 22041175] | Ligand Activity Charts

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compound 7c [PMID: 22041175]
Ligand Activity Charts

compound 7c [PMID: 22041175] [Ligand Id: 9931] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1962788
NADPH oxidase 1 in Human [GtoPdb: 3001] [UniProtKB: Q9Y5S8] There should be some charts here, you may need to enable JavaScript!
cytochrome b-245 beta chain in Human [GtoPdb: 3002] [UniProtKB: P04839] There should be some charts here, you may need to enable JavaScript!
NADPH oxidase 4 in Human [GtoPdb: 3004] [UniProtKB: Q9NPH5] There should be some charts here, you may need to enable JavaScript!
NADPH oxidase 5 in Human [GtoPdb: 3005] [UniProtKB: Q96PH1] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
NADPH oxidase 1 in Human [GtoPdb: 3001] [UniProtKB: Q9Y5S8]
GtoPdb	-	-	7	pKi	101	nM	Ki	Bioorg Med Chem (2011) 19: 6989-99 [PMID:22041175]
cytochrome b-245 beta chain in Human [GtoPdb: 3002] [UniProtKB: P04839]
GtoPdb	-	-	5.87	pKi	1340	nM	Ki	Bioorg Med Chem (2011) 19: 6989-99 [PMID:22041175]
NADPH oxidase 4 in Human [GtoPdb: 3004] [UniProtKB: Q9NPH5]
GtoPdb	-	-	7.14	pKi	72	nM	Ki	Bioorg Med Chem (2011) 19: 6989-99 [PMID:22041175]
NADPH oxidase 5 in Human [GtoPdb: 3005] [UniProtKB: Q96PH1]
GtoPdb	-	-	6.38	pKi	414	nM	Ki	Bioorg Med Chem (2011) 19: 6989-99 [PMID:22041175]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]