marbostat-100 [Ligand Id: 9891] activity data from GtoPdb

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  • histone deacetylase 2 in Human [GtoPdb: 2616] [UniProtKB: Q92769]
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  • histone deacetylase 6 in Human [GtoPdb: 2618] [UniProtKB: Q9UBN7]
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  • histone deacetylase 8 in Human [GtoPdb: 2619] [UniProtKB: Q9BY41]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
histone deacetylase 2 in Human [GtoPdb: 2616] [UniProtKB: Q92769]
GtoPdb In vitro biochemical assay using recombinant purified human HDAC2. - 6.11 pKi 774 nM Ki J Med Chem (2018) 61: 3454-3477 [PMID:29589441]
histone deacetylase 6 in Human [GtoPdb: 2618] [UniProtKB: Q9UBN7]
GtoPdb In vitro biochemical assay using recombinant purified human HDAC6. - 9.15 pKi 0.7 nM Ki J Med Chem (2018) 61: 3454-3477 [PMID:29589441]
histone deacetylase 8 in Human [GtoPdb: 2619] [UniProtKB: Q9BY41]
GtoPdb In vitro biochemical assay using recombinant purified human HDAC8. - 6.76 pKi 173 nM Ki J Med Chem (2018) 61: 3454-3477 [PMID:29589441]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.