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ChEMBL ligand: CHEMBL3741938 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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signal transducer and activator of transcription 6/Signal transducer and activator of transcription 6 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5401] [GtoPdb: 2993] [UniProtKB: P42226] | ||||||||
GtoPdb | Inhibition of STAT6 expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence polarization assay. | - | 7.55 | pIC50 | 28 | nM | IC50 | J Med Chem (2015) 58: 8970-84 [PMID:26506089] |
ChEMBL | Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence polarization assay | B | 7.55 | pIC50 | 28 | nM | IC50 | J Med Chem (2015) 58: 8970-8984 [PMID:26506089] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]