compound 19a [PMID: 26506089] [Ligand Id: 9842] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL3741938
  • signal transducer and activator of transcription 6/Signal transducer and activator of transcription 6 in Human [ChEMBL: CHEMBL5401] [GtoPdb: 2993] [UniProtKB: P42226]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
signal transducer and activator of transcription 6/Signal transducer and activator of transcription 6 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5401] [GtoPdb: 2993] [UniProtKB: P42226]
GtoPdb Inhibition of STAT6 expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence polarization assay. - 7.55 pIC50 28 nM IC50 J Med Chem (2015) 58: 8970-84 [PMID:26506089]
ChEMBL Inhibition of STAT6 (unknown origin) expressed in Escherichia coli using FAM-Ala-pTyr-Lys-ProPhe-Gln-Asp-Leu-Ile-NH2 as substrate by fluorescence polarization assay B 7.55 pIC50 28 nM IC50 J. Med. Chem. (2015) 58: 8970-8984 [PMID:26506089]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]