CCT241161 [Ligand Id: 9814] activity data from GtoPdb

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  • B-Raf proto-oncogene, serine/threonine kinase in Human [GtoPdb: 1943] [UniProtKB: P15056]
Created with Highcharts 10.3.3ValuesChart context menuB-Raf proto-oncogene, serine/threonine kinasepKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • LCK proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2053] [UniProtKB: P06239]
Created with Highcharts 10.3.3ValuesChart context menuLCK proto-oncogene, Src family tyrosine kinasepKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • Raf-1 proto-oncogene, serine/threonine kinase in Human [GtoPdb: 2184] [UniProtKB: P04049]
Created with Highcharts 10.3.3ValuesChart context menuRaf-1 proto-oncogene, serine/threonine kinasepKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • SRC proto-oncogene, non-receptor tyrosine kinase in Human [GtoPdb: 2206] [UniProtKB: P12931]
Created with Highcharts 10.3.3ValuesChart context menuSRC proto-oncogene, non-receptor tyrosine kinasepKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
B-Raf proto-oncogene, serine/threonine kinase in Human [GtoPdb: 1943] [UniProtKB: P15056]
GtoPdb - - 7.52 pIC50 30 nM IC50 Cancer Cell (2015) 27: 85-96 [PMID:25500121]
LCK proto-oncogene, Src family tyrosine kinase in Human [GtoPdb: 2053] [UniProtKB: P06239]
GtoPdb - - 8.52 pIC50 3 nM IC50 Cancer Cell (2015) 27: 85-96 [PMID:25500121]
Raf-1 proto-oncogene, serine/threonine kinase in Human [GtoPdb: 2184] [UniProtKB: P04049]
GtoPdb - - 8.22 pIC50 6 nM IC50 Cancer Cell (2015) 27: 85-96 [PMID:25500121]
SRC proto-oncogene, non-receptor tyrosine kinase in Human [GtoPdb: 2206] [UniProtKB: P12931]
GtoPdb - - 8 pIC50 10 nM IC50 Cancer Cell (2015) 27: 85-96 [PMID:25500121]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.