growth differentiation factor 15 [Ligand Id: 9735] activity data from GtoPdb

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

  • GDNF family receptor alpha like in Human [GtoPdb: 2977] [UniProtKB: Q6UXV0]
Created with Highcharts 10.3.3ValuesChart context menuGDNF family receptor alpha likepKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
GDNF family receptor alpha like in Human [GtoPdb: 2977] [UniProtKB: Q6UXV0]
GtoPdb Native GDF15 binding to the extracellular domain of GFRAL in vitro. - 7.6 pKd 25 nM Kd Nat Med (2017) 23: 1215-1219 [PMID:28846098]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.