asivatrep [Ligand Id: 9621] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL3707398 (Asivatrep, Pac-14028)
  • TRPV1 in Rat [GtoPdb: 507] [UniProtKB: O35433]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
TRPV1 in Rat [GtoPdb: 507] [UniProtKB: O35433]
GtoPdb Antagonism of capsaicin-induced calcium influx in isolated primary rat spinal dorsal root ganglia cells. - 8.21 pIC50 6.2 nM IC50 US7858621. Compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same (2010)

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]