zyklophin [Ligand Id: 9193] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL574568
  • δ receptor in Human [GtoPdb: 317] [UniProtKB: P41143]
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  • κ receptor in Human [GtoPdb: 318] [UniProtKB: P41145]
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  • μ receptor in Human [GtoPdb: 319] [UniProtKB: P35372]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
δ receptor in Human [GtoPdb: 317] [UniProtKB: P41143]
GtoPdb - - 5 pKi >10000 nM Ki J Med Chem (2005) 48: 4500-3 [PMID:15999987]
κ receptor in Human [GtoPdb: 318] [UniProtKB: P41145]
GtoPdb - - 7.52 pKi 30.3 nM Ki J Med Chem (2005) 48: 4500-3 [PMID:15999987]
μ receptor in Human [GtoPdb: 319] [UniProtKB: P35372]
GtoPdb - - 5.23 pKi 5880 nM Ki J Med Chem (2005) 48: 4500-3 [PMID:15999987]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]