urocortin 1 [Ligand Id: 919] activity data from GtoPdb

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  • CRF1 receptor in Human [GtoPdb: 212] [UniProtKB: P34998]
Created with Highcharts 10.3.3ValuesChart context menuCRF1 receptorpKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • CRF2 receptor in Human [GtoPdb: 213] [UniProtKB: Q13324]
  • CRF2 receptor in Mouse [GtoPdb: 213] [UniProtKB: Q60748]
  • CRF2 receptor in Rat [GtoPdb: 213] [UniProtKB: P47866]
Created with Highcharts 10.3.3ValuesChart context menuCRF2 receptorpKd HumanpKi HumanpIC50 HumanpEC50 HumanpKd MousepKi MousepIC50 MousepEC50 MousepKd RatpKi RatpIC50 RatpEC50 Rat024681012Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CRF1 receptor in Human [GtoPdb: 212] [UniProtKB: P34998]
GtoPdb - - 9.5 pKd - - - Biochem Pharmacol (2004) 68: 1833-1844 [PMID:15450949];
J Pharmacol Exp Ther (2001) 296: 113-20 [PMID:11123370];
Endocrinology (1996) 137: 2167-70 [PMID:8612563]
CRF2 receptor in Human [GtoPdb: 213] [UniProtKB: Q13324]
GtoPdb - - 9.6 pKd - - - Biochem Pharmacol (2004) 68: 1833-1844 [PMID:15450949];
J Pharmacol Exp Ther (2001) 296: 113-20 [PMID:11123370]
CRF2 receptor in Mouse [GtoPdb: 213] [UniProtKB: Q60748]
GtoPdb - - 8.8 pKd - - - Endocrinology (1996) 137: 2167-70 [PMID:8612563]
CRF2 receptor in Rat [GtoPdb: 213] [UniProtKB: P47866]
GtoPdb - - 8.7 pKd - - - Endocrinology (1996) 137: 2167-70 [PMID:8612563]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.