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ChEMBL ligand: CHEMBL270575 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Glucocorticoid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2034] [GtoPdb: 625] [UniProtKB: P04150] | ||||||||
GtoPdb | - | - | 9.15 | pKi | 0.7 | nM | Ki | Bioorg Med Chem Lett (2008) 18: 1312-7 [PMID:18226897] |
ChEMBL | Displacement of [3H]dexamethasone from human recombinant GR | B | 9.15 | pKi | 0.7 | nM | Ki | Bioorg. Med. Chem. Lett. (2008) 18: 1312-1317 [PMID:18226897] |
ChEMBL | Antagonist activity at GR in SW1353/MMTV5 cells assessed as inhibition of dexamethasone-induced luciferase expression | F | 9.22 | pKi | 0.6 | nM | Ki | Bioorg. Med. Chem. Lett. (2008) 18: 1312-1317 [PMID:18226897] |
ChEMBL data shown on this page come from version 28:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]