C108297 [Ligand Id: 9180] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL270575 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Glucocorticoid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2034] [GtoPdb: 625] [UniProtKB: P04150] | ||||||||
| GtoPdb | - | - | 9.15 | pKi | 0.7 | nM | Ki | Bioorg Med Chem Lett (2008) 18: 1312-7 [PMID:18226897] |
| ChEMBL | Displacement of [3H]dexamethasone from human recombinant GR | B | 9.15 | pKi | 0.7 | nM | Ki | Bioorg Med Chem Lett (2008) 18: 1312-1317 [PMID:18226897] |
| ChEMBL | Antagonist activity at GR in SW1353/MMTV5 cells assessed as inhibition of dexamethasone-induced luciferase expression | F | 9.22 | pKi | 0.6 | nM | Ki | Bioorg Med Chem Lett (2008) 18: 1312-1317 [PMID:18226897] |
ChEMBL data shown on this page come from version 35:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
