AZD5069 [Ligand Id: 8948] activity data from GtoPdb

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  • CXCR1 in Human [GtoPdb: 68] [UniProtKB: P25024]
  • This target only has 0 pki data point
1 _lig_chart_1 CXCR1 Human
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  • CXCR2 in Human [GtoPdb: 69] [UniProtKB: P25025]
  • This target only has 0 pki data point
2 _lig_chart_2 CXCR2 Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CXCR1 in Human [GtoPdb: 68] [UniProtKB: P25024]
GtoPdb Measuring displacement of CXCL8 binding to recombinant CXCR1 in HEK cell membrane preparations. - 6.9 pIC50 125 nM IC50 J. Pharmacol. Exp. Ther. (2015) 353: 340-50 [PMID:25736418]
CXCR2 in Human [GtoPdb: 69] [UniProtKB: P25025]
GtoPdb Measuring displacement of CXCL8 binding to recombinant CXCR2 in HEK cell membrane preparations. - 9.1 pIC50 0.79 nM IC50 J. Pharmacol. Exp. Ther. (2015) 353: 340-50 [PMID:25736418]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.