JNJ-46281222 [Ligand Id: 8947] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| mGlu2 receptor in Human [GtoPdb: 290] [UniProtKB: Q14416] | ||||||||
| GtoPdb | Saturation binding experiment using tritiated compound, and membranes from CHO-K1 cells stably expressing the human mGlu2 receptor. | - | 8.77 | pKd | 1.7 | nM | Kd | Br J Pharmacol (2016) 173: 588-600 [PMID:26589404] |
| GtoPdb | Homologous displacement assay. | - | 8.33 | pKi | 4.68 | nM | Ki | Br J Pharmacol (2016) 173: 588-600 [PMID:26589404] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
