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ChEMBL ligand: CHEMBL16044 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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nicotinic acetylcholine receptor δ subunit/Acetylcholine receptor protein delta chain in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3011] [GtoPdb: 476] [UniProtKB: Q07001] | ||||||||
ChEMBL | Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expressed in TE-671 cell (at holding potential -50 mV) | B | 6.24 | pIC50 | 580 | nM | IC50 | Bioorg Med Chem Lett (2002) 12: 1159-1162 [PMID:11934578] |
ChEMBL | Compound was evaluated for inhibitory activity against human embryonic muscle type Nicotinic acetylcholine receptor specifically delta-subunit expressed in TE-671 cell (at holding potential -100 mV) | B | 6.34 | pIC50 | 460 | nM | IC50 | Bioorg Med Chem Lett (2002) 12: 1159-1162 [PMID:11934578] |
GtoPdb | - | - | 6.34 | pIC50 | 460 | nM | IC50 | Bioorg Med Chem Lett (2002) 12: 1159-62 [PMID:11934578] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]