SR16835 [Ligand Id: 8867] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL3262554 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| κ receptor in Human [GtoPdb: 318] [UniProtKB: P41145] | ||||||||
| GtoPdb | Radioligand binding assay | - | 6.17 | pKi | 681.3 | nM | Ki | J Pharmacol Exp Ther (2009) 331: 954-64 [PMID:19773529] |
| μ receptor in Human [GtoPdb: 319] [UniProtKB: P35372] | ||||||||
| GtoPdb | Radioligand binding assay | - | 7.1 | pKi | 79.9 | nM | Ki | J Pharmacol Exp Ther (2009) 331: 954-64 [PMID:19773529] |
| NOP receptor in Human [GtoPdb: 320] [UniProtKB: P41146] | ||||||||
| GtoPdb | Radioligand binding assay | - | 7.94 | pKi | 11.4 | nM | Ki | J Pharmacol Exp Ther (2009) 331: 954-64 [PMID:19773529] |
| GtoPdb | Stimulation of GTP-γ35S binding | - | 7.34 | pEC50 | 46.1 | nM | EC50 | J Pharmacol Exp Ther (2009) 331: 954-64 [PMID:19773529] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
