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ChEMBL ligand: CHEMBL515637 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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sPLA2-2D/Group IID secretory phospholipase A2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4281] [GtoPdb: 1418] [UniProtKB: Q9UNK4] | ||||||||
GtoPdb | - | - | 8.15 | pIC50 | 7 | nM | IC50 | J Med Chem (2008) 51: 4708-14 [PMID:18605714] |
ChEMBL | Inhibition of human group2D phospholipase A2 by [3H]oleic acid-labeled Escherichia coli membrane assay | B | 8.15 | pIC50 | 7 | nM | IC50 | J Med Chem (2008) 51: 4708-4714 [PMID:18605714] |
sPLA2-2D/Group IID secretory phospholipase A2 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5537] [GtoPdb: 1418] [UniProtKB: Q9WVF6] | ||||||||
ChEMBL | Inhibition of mouse group2D phospholipase A2 fluorimetric assay | B | 6.49 | pIC50 | 320 | nM | IC50 | J Med Chem (2008) 51: 4708-4714 [PMID:18605714] |
sPLA2-2E/Group IIE secretory phospholipase A2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2154] [GtoPdb: 1419] [UniProtKB: Q9NZK7] | ||||||||
GtoPdb | - | - | 8.15 | pIC50 | 7 | nM | IC50 | J Med Chem (2008) 51: 4708-14 [PMID:18605714] |
ChEMBL | Inhibition of human group2E phospholipase A2 fluorimetric assay | B | 8.15 | pIC50 | 7 | nM | IC50 | J Med Chem (2008) 51: 4708-4714 [PMID:18605714] |
sPLA2-2E/Group IIE secretory phospholipase A2 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4201] [GtoPdb: 1419] [UniProtKB: Q9QUL3] | ||||||||
ChEMBL | Inhibition of mouse group2E phospholipase A2 fluorimetric assay | B | 7.74 | pIC50 | 18 | nM | IC50 | J Med Chem (2008) 51: 4708-4714 [PMID:18605714] |
sPLA2-2F/Group IIF secretory phospholipase A2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4278] [GtoPdb: 1420] [UniProtKB: Q9BZM2] | ||||||||
GtoPdb | - | - | 7.3 | pIC50 | 50 | nM | IC50 | J Med Chem (2008) 51: 4708-14 [PMID:18605714] |
ChEMBL | Inhibition of human group2F phospholipase A2 fluorimetric assay | B | 7.3 | pIC50 | 50 | nM | IC50 | J Med Chem (2008) 51: 4708-4714 [PMID:18605714] |
sPLA2-2F/Group IIF secretory phospholipase A2 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5361] [GtoPdb: 1420] [UniProtKB: Q9QZT4] | ||||||||
ChEMBL | Inhibition of mouse group2F phospholipase A2 fluorimetric assay | B | 6.77 | pIC50 | 170 | nM | IC50 | J Med Chem (2008) 51: 4708-4714 [PMID:18605714] |
sPLA2-10/Group X secretory phospholipase A2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4342] [GtoPdb: 1422] [UniProtKB: O15496] | ||||||||
ChEMBL | Inhibition of human group2X phospholipase A2 fluorimetric assay | B | 7.7 | pIC50 | 20 | nM | IC50 | J Med Chem (2008) 51: 4708-4714 [PMID:18605714] |
GtoPdb | - | - | 7.7 | pIC50 | 20 | nM | IC50 | J Med Chem (2008) 51: 4708-14 [PMID:18605714] |
sPLA2-10/Group X secretory phospholipase A2 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4200] [GtoPdb: 1422] [UniProtKB: Q9QXX3] | ||||||||
ChEMBL | Inhibition of mouse group2X phospholipase A2 fluorimetric assay | B | 8.22 | pIC50 | 6 | nM | IC50 | J Med Chem (2008) 51: 4708-4714 [PMID:18605714] |
sPLA2-1B/Phospholipase A2 group 1B in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4426] [GtoPdb: 1416] [UniProtKB: P04054] | ||||||||
ChEMBL | Inhibition of human group1B phospholipase A2 fluorimetric assay | B | 7.08 | pIC50 | 84 | nM | IC50 | J Med Chem (2008) 51: 4708-4714 [PMID:18605714] |
GtoPdb | - | - | 7.08 | pIC50 | 84 | nM | IC50 | J Med Chem (2008) 51: 4708-14 [PMID:18605714] |
sPLA2-1B/Phospholipase A2 group 1B in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4378] [GtoPdb: 1416] [UniProtKB: Q9Z0Y2] | ||||||||
ChEMBL | Inhibition of mouse group1B phospholipase A2 fluorimetric assay | B | 6.8 | pIC50 | 160 | nM | IC50 | J Med Chem (2008) 51: 4708-4714 [PMID:18605714] |
sPLA2-2A/Phospholipase A2 group IIA in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3474] [GtoPdb: 1417] [UniProtKB: P14555] | ||||||||
ChEMBL | Inhibition of human group2A phospholipase A2 fluorimetric assay | B | 7.4 | pIC50 | 40 | nM | IC50 | J Med Chem (2008) 51: 4708-4714 [PMID:18605714] |
GtoPdb | - | - | 7.4 | pIC50 | 40 | nM | IC50 | J Med Chem (2008) 51: 4708-14 [PMID:18605714] |
PLA2-G5/Phospholipase A2 group V in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4323] [GtoPdb: 1430] [UniProtKB: P39877] | ||||||||
ChEMBL | Inhibition of human group2V phospholipase A2 fluorimetric assay | B | 7.46 | pIC50 | 35 | nM | IC50 | J Med Chem (2008) 51: 4708-4714 [PMID:18605714] |
GtoPdb | - | - | 7.46 | pIC50 | 35 | nM | IC50 | J Med Chem (2008) 51: 4708-14 [PMID:18605714] |
PLA2-G5/Phospholipase A2 group V in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4167] [GtoPdb: 1430] [UniProtKB: P97391] | ||||||||
ChEMBL | Inhibition of mouse group2V phospholipase A2 fluorimetric assay | B | 7.7 | pIC50 | 20 | nM | IC50 | J Med Chem (2008) 51: 4708-4714 [PMID:18605714] |
sPLA2-2A in Human [GtoPdb: 1417] [UniProtKB: P14555] | ||||||||
GtoPdb | - | - | 7.4 | pIC50 | 40 | nM | IC50 | J Med Chem (2008) 51: 4708-14 [PMID:18605714] |
sPLA2-2A/Phospholipase A2, membrane associated in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5761] [GtoPdb: 1417] [UniProtKB: P31482] | ||||||||
ChEMBL | Inhibition of mouse group2A phospholipase A2 fluorimetric assay | B | 7.52 | pIC50 | 30 | nM | IC50 | J Med Chem (2008) 51: 4708-4714 [PMID:18605714] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]