ChEMBL ligand: CHEMBL3218011
Rho associated coiled-coil containing protein kinase 1 in Human [GtoPdb: 1503] [UniProtKB: Q13464] There should be some charts here, you may need to enable JavaScript!
Rho associated coiled-coil containing protein kinase 2 in Human [GtoPdb: 1504] [UniProtKB: O75116] There should be some charts here, you may need to enable JavaScript!
DM1 protein kinase in Human [GtoPdb: 1505] [UniProtKB: Q09013] There should be some charts here, you may need to enable JavaScript!
CDC42 binding protein kinase alpha in Human [GtoPdb: 1507] [UniProtKB: Q5VT25] There should be some charts here, you may need to enable JavaScript!
protein kinase N1 in Human [GtoPdb: 1520] [UniProtKB: Q16512] There should be some charts here, you may need to enable JavaScript!
myosin light chain kinase in Human [GtoPdb: 1552] [UniProtKB: Q15746] There should be some charts here, you may need to enable JavaScript!
LIM domain kinase 1 in Human [GtoPdb: 2054] [UniProtKB: P53667] There should be some charts here, you may need to enable JavaScript!
p21 (RAC1) activated kinase 1 in Human [GtoPdb: 2133] [UniProtKB: Q13153] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Rho associated coiled-coil containing protein kinase 1 in Human [GtoPdb: 1503] [UniProtKB: Q13464]
GtoPdb	-	-	9	pIC50	<1	nM	IC50	Medchemcomm (2012) 3: 699-709 [PMID:23275831]
Rho associated coiled-coil containing protein kinase 2 in Human [GtoPdb: 1504] [UniProtKB: O75116]
GtoPdb	-	-	9	pIC50	<1	nM	IC50	Medchemcomm (2012) 3: 699-709 [PMID:23275831]
DM1 protein kinase in Human [GtoPdb: 1505] [UniProtKB: Q09013]
GtoPdb	-	-	7.47	pIC50	34.06	nM	IC50	Medchemcomm (2012) 3: 699-709 [PMID:23275831]
CDC42 binding protein kinase alpha in Human [GtoPdb: 1507] [UniProtKB: Q5VT25]
GtoPdb	-	-	8.54	pIC50	2.87	nM	IC50	Medchemcomm (2012) 3: 699-709 [PMID:23275831]
protein kinase N1 in Human [GtoPdb: 1520] [UniProtKB: Q16512]
GtoPdb	-	-	9	pIC50	<1	nM	IC50	Medchemcomm (2012) 3: 699-709 [PMID:23275831]
myosin light chain kinase in Human [GtoPdb: 1552] [UniProtKB: Q15746]
GtoPdb	-	-	7.81	pIC50	15.63	nM	IC50	Medchemcomm (2012) 3: 699-709 [PMID:23275831]
LIM domain kinase 1 in Human [GtoPdb: 2054] [UniProtKB: P53667]
GtoPdb	-	-	8.76	pIC50	1.74	nM	IC50	Medchemcomm (2012) 3: 699-709 [PMID:23275831]
p21 (RAC1) activated kinase 1 in Human [GtoPdb: 2133] [UniProtKB: Q13153]
GtoPdb	-	-	9	pIC50	<1	nM	IC50	Medchemcomm (2012) 3: 699-709 [PMID:23275831]

ChEMBL data shown on this page come from version 36:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]