ChEMBL ligand: CHEMBL566515
EPH receptor A1 in Human [GtoPdb: 1821] [UniProtKB: P21709] There should be some charts here, you may need to enable JavaScript!
EPH receptor A2 in Human [GtoPdb: 1822] [UniProtKB: P29317] There should be some charts here, you may need to enable JavaScript!
EPH receptor A3 in Human [GtoPdb: 1823] [UniProtKB: P29320] There should be some charts here, you may need to enable JavaScript!
EPH receptor A4 in Human [GtoPdb: 1824] [UniProtKB: P54764] There should be some charts here, you may need to enable JavaScript!
EPH receptor A5 in Human [GtoPdb: 1825] [UniProtKB: P54756] There should be some charts here, you may need to enable JavaScript!
EPH receptor A7 in Human [GtoPdb: 1827] [UniProtKB: Q15375] There should be some charts here, you may need to enable JavaScript!
EPH receptor A8 in Human [GtoPdb: 1828] [UniProtKB: P29322] There should be some charts here, you may need to enable JavaScript!
EPH receptor B1 in Human [GtoPdb: 1830] [UniProtKB: P54762] There should be some charts here, you may need to enable JavaScript!
EPH receptor B2 in Human [GtoPdb: 1831] [UniProtKB: P29323] There should be some charts here, you may need to enable JavaScript!
EPH receptor B3 in Human [GtoPdb: 1832] [UniProtKB: P54753] There should be some charts here, you may need to enable JavaScript!
EPH receptor B4 in Human [GtoPdb: 1833] [UniProtKB: P54760] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
EPH receptor A1 in Human [GtoPdb: 1821] [UniProtKB: P21709]
GtoPdb	-	-	8.54	pIC50	2.9	nM	IC50	J Med Chem (2009) 52: 6433-46 [PMID:19788238]
EPH receptor A2 in Human [GtoPdb: 1822] [UniProtKB: P29317]
GtoPdb	-	-	8.64	pIC50	2.3	nM	IC50	J Med Chem (2009) 52: 6433-46 [PMID:19788238]
EPH receptor A3 in Human [GtoPdb: 1823] [UniProtKB: P29320]
GtoPdb	-	-	7.4	pIC50	40	nM	IC50	J Med Chem (2009) 52: 6433-46 [PMID:19788238]
EPH receptor A4 in Human [GtoPdb: 1824] [UniProtKB: P54764]
GtoPdb	-	-	8.48	pIC50	3.3	nM	IC50	J Med Chem (2009) 52: 6433-46 [PMID:19788238]
EPH receptor A5 in Human [GtoPdb: 1825] [UniProtKB: P54756]
GtoPdb	-	-	8.52	pIC50	3	nM	IC50	J Med Chem (2009) 52: 6433-46 [PMID:19788238]
EPH receptor A7 in Human [GtoPdb: 1827] [UniProtKB: Q15375]
GtoPdb	-	-	5.95	pIC50	1118	nM	IC50	J Med Chem (2009) 52: 6433-46 [PMID:19788238]
EPH receptor A8 in Human [GtoPdb: 1828] [UniProtKB: P29322]
GtoPdb	-	-	8.35	pIC50	4.5	nM	IC50	J Med Chem (2009) 52: 6433-46 [PMID:19788238]
EPH receptor B1 in Human [GtoPdb: 1830] [UniProtKB: P54762]
GtoPdb	-	-	8.96	pIC50	1.1	nM	IC50	J Med Chem (2009) 52: 6433-46 [PMID:19788238]
EPH receptor B2 in Human [GtoPdb: 1831] [UniProtKB: P29323]
GtoPdb	-	-	8.92	pIC50	1.2	nM	IC50	J Med Chem (2009) 52: 6433-46 [PMID:19788238]
EPH receptor B3 in Human [GtoPdb: 1832] [UniProtKB: P54753]
GtoPdb	-	-	7.82	pIC50	15	nM	IC50	J Med Chem (2009) 52: 6433-46 [PMID:19788238]
EPH receptor B4 in Human [GtoPdb: 1833] [UniProtKB: P54760]
GtoPdb	-	-	8.8	pIC50	1.6	nM	IC50	J Med Chem (2009) 52: 6433-46 [PMID:19788238]

ChEMBL data shown on this page come from version 36:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]