ChEMBL ligand: CHEMBL2322989
EPH receptor A1 in Human [GtoPdb: 1821] [UniProtKB: P21709] There should be some charts here, you may need to enable JavaScript!
EPH receptor A2 in Mouse [GtoPdb: 1822] [UniProtKB: Q03145] There should be some charts here, you may need to enable JavaScript!
EPH receptor A3 in Mouse [GtoPdb: 1823] [UniProtKB: P29319] There should be some charts here, you may need to enable JavaScript!
EPH receptor A4 in Mouse [GtoPdb: 1824] [UniProtKB: Q03137] There should be some charts here, you may need to enable JavaScript!
EPH receptor A5 in Rat [GtoPdb: 1825] [UniProtKB: P54757] There should be some charts here, you may need to enable JavaScript!
EPH receptor A6 in Mouse [GtoPdb: 1826] [UniProtKB: Q62413] There should be some charts here, you may need to enable JavaScript!
EPH receptor A7 in Mouse [GtoPdb: 1827] [UniProtKB: Q61772] There should be some charts here, you may need to enable JavaScript!
EPH receptor A8 in Mouse [GtoPdb: 1828] [UniProtKB: O09127] There should be some charts here, you may need to enable JavaScript!
EPH receptor B1 in Rat [GtoPdb: 1830] [UniProtKB: P09759] There should be some charts here, you may need to enable JavaScript!
EPH receptor B2 in Mouse [GtoPdb: 1831] [UniProtKB: P54763] There should be some charts here, you may need to enable JavaScript!
EPH receptor B3 in Mouse [GtoPdb: 1832] [UniProtKB: P54754] There should be some charts here, you may need to enable JavaScript!
EPH receptor B4 in Mouse [GtoPdb: 1833] [UniProtKB: P54761] There should be some charts here, you may need to enable JavaScript!
EPH receptor B6 in Mouse [GtoPdb: 1834] [UniProtKB: O08644] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
EPH receptor A1 in Human [GtoPdb: 1821] [UniProtKB: P21709]
GtoPdb	-	-	5.64	pIC50	2300	nM	IC50	J Med Chem (2013) 56: 2936-47 [PMID:23489211]
EPH receptor A2 in Mouse [GtoPdb: 1822] [UniProtKB: Q03145]
GtoPdb	-	-	5.66	pIC50	2200	nM	IC50	J Med Chem (2013) 56: 2936-47 [PMID:23489211]
EPH receptor A3 in Mouse [GtoPdb: 1823] [UniProtKB: P29319]
GtoPdb	-	-	5.6	pIC50	2500	nM	IC50	J Med Chem (2013) 56: 2936-47 [PMID:23489211]
EPH receptor A4 in Mouse [GtoPdb: 1824] [UniProtKB: Q03137]
GtoPdb	-	-	5.57	pIC50	2700	nM	IC50	J Med Chem (2013) 56: 2936-47 [PMID:23489211]
EPH receptor A5 in Rat [GtoPdb: 1825] [UniProtKB: P54757]
GtoPdb	-	-	5.62	pIC50	2400	nM	IC50	J Med Chem (2013) 56: 2936-47 [PMID:23489211]
EPH receptor A6 in Mouse [GtoPdb: 1826] [UniProtKB: Q62413]
GtoPdb	-	-	5.82	pIC50	1500	nM	IC50	J Med Chem (2013) 56: 2936-47 [PMID:23489211]
EPH receptor A7 in Mouse [GtoPdb: 1827] [UniProtKB: Q61772]
GtoPdb	-	-	5.68	pIC50	2100	nM	IC50	J Med Chem (2013) 56: 2936-47 [PMID:23489211]
EPH receptor A8 in Mouse [GtoPdb: 1828] [UniProtKB: O09127]
GtoPdb	-	-	5.82	pIC50	1500	nM	IC50	J Med Chem (2013) 56: 2936-47 [PMID:23489211]
EPH receptor B1 in Rat [GtoPdb: 1830] [UniProtKB: P09759]
GtoPdb	-	-	5.42	pIC50	3800	nM	IC50	J Med Chem (2013) 56: 2936-47 [PMID:23489211]
EPH receptor B2 in Mouse [GtoPdb: 1831] [UniProtKB: P54763]
GtoPdb	-	-	5.42	pIC50	3800	nM	IC50	J Med Chem (2013) 56: 2936-47 [PMID:23489211]
EPH receptor B3 in Mouse [GtoPdb: 1832] [UniProtKB: P54754]
GtoPdb	-	-	5.36	pIC50	4400	nM	IC50	J Med Chem (2013) 56: 2936-47 [PMID:23489211]
EPH receptor B4 in Mouse [GtoPdb: 1833] [UniProtKB: P54761]
GtoPdb	-	-	5.36	pIC50	4400	nM	IC50	J Med Chem (2013) 56: 2936-47 [PMID:23489211]
EPH receptor B6 in Mouse [GtoPdb: 1834] [UniProtKB: O08644]
GtoPdb	-	-	5.24	pIC50	5800	nM	IC50	J Med Chem (2013) 56: 2936-47 [PMID:23489211]

ChEMBL data shown on this page come from version 36:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]