thiotepa [Ligand Id: 7622] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL671 (NSC-6396, Tepadina, Thioplex, Thiotepa)
  • CYP2B6 in Human [GtoPdb: 1324] [UniProtKB: P20813]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CYP2B6 in Human [GtoPdb: 1324] [UniProtKB: P20813]
GtoPdb - - 5.32 pKi 4800 nM Ki Drug Metab Dispos (2007) 35: 2053-9 [PMID:17682072]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]