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ChEMBL ligand: CHEMBL2104981 (Rilapladib, SB-659032) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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PLA2-G7/LDL-associated phospholipase A2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3514] [GtoPdb: 1432] [UniProtKB: Q13093] | ||||||||
ChEMBL | Inhibition of LpPLA2 (unknown origin) | B | 9.6 | pIC50 | 0.25 | nM | IC50 | ACS Med Chem Lett (2017) 8: 43-48 [PMID:28105273] |
GtoPdb | - | - | 9.64 | pIC50 | 0.23 | nM | IC50 | Curr Opin Lipidol (2009) 20: 415-20 [PMID:19667981] |
ChEMBL data shown on this page come from version 28:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]