etazolate [Ligand Id: 7336] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL356388 (EHT-0202, Etazolate, SQ-20009) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| phosphodiesterase 4D/Phosphodiesterase 4D in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL288] [GtoPdb: 1303] [UniProtKB: Q08499] | ||||||||
| ChEMBL | Inhibition of PDE4D3 (unknown origin) | B | 6.41 | pIC50 | 390 | nM | IC50 | J Med Chem (2020) 63: 10594-10617 [PMID:32255344] |
| GABAA receptor β3 subunit in Human [GtoPdb: 412] [UniProtKB: P28472] | ||||||||
| GtoPdb | inhibition of [35S]TBPS binding | - | 5.46 | pIC50 | 3500 | nM | IC50 | Eur J Pharmacol (1996) 301: 207-14 [PMID:8773466] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
