Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
---|---|---|---|---|---|---|---|---|
CaS receptor in Human [GtoPdb: 54] [UniProtKB: P41180] | ||||||||
GtoPdb | - | - | 2.4 | pKd | - | - | - | J Biol Chem (1995) 270: 2755-63 [PMID:7531693] |
CaS receptor in Mouse [GtoPdb: 54] [UniProtKB: Q9QY96] | ||||||||
GtoPdb | - | - | 2.5 | pKd | - | - | - | J Biol Chem (2005) 280: 40201-9 [PMID:16199532] |
CaS receptor in Rat [GtoPdb: 54] [UniProtKB: P48442] | ||||||||
GtoPdb | - | - | 2.5 | pKd | - | - | - | Proc Natl Acad Sci USA (1995) 92: 131-5 [PMID:7816802] |
KCa2.1 in Human [GtoPdb: 381] [UniProtKB: Q92952] | ||||||||
GtoPdb | - | - | 6.52 | pEC50 | 300 | nM | EC50 |
Science (1996) 273: 1709-14 [PMID:8781233]; Nature (1998) 395: 503-7 [PMID:9774106] |
KCa2.2 in Human [GtoPdb: 382] [UniProtKB: Q9H2S1] | ||||||||
GtoPdb | - | - | 6.5 | pEC50 | - | - | - |
Nature (1998) 395: 503-7 [PMID:9774106]; J Biol Chem (2005) 280: 41404-11 [PMID:16239218]; J Biol Chem (2000) 275: 39954-63 [PMID:10991935] |
KCa2.2 in Rat [GtoPdb: 382] [UniProtKB: P70604] | ||||||||
GtoPdb | - | - | 6.4 | pEC50 | - | - | - |
Science (1996) 273: 1709-14 [PMID:8781233]; J Gen Physiol (1998) 111: 565-81 [PMID:9524139] |
KCa2.3 in Human [GtoPdb: 383] [UniProtKB: Q9UGI6] | ||||||||
GtoPdb | - | - | 6.5 | pEC50 | - | - | - |
Nature (1998) 395: 503-7 [PMID:9774106]; Br J Pharmacol (2007) 151: 655-65 [PMID:17486140]; Mol Pharmacol (2004) 65: 788-801 [PMID:14978258] |
KCa2.3 in Rat [GtoPdb: 383] [UniProtKB: P70605] | ||||||||
GtoPdb | - | - | 6.2 | pEC50 | - | - | - | Am J Physiol, Cell Physiol (2001) 280: C836-42 [PMID:11245600] |
KCa3.1 in Human [GtoPdb: 384] [UniProtKB: O15554] | ||||||||
GtoPdb | - | - | 7 | pEC50 | - | - | - |
Proc Natl Acad Sci USA (1997) 94: 11651-6 [PMID:9326665]; Proc Natl Acad Sci USA (1997) 94: 11013-8 [PMID:9380751]; Am J Physiol, Cell Physiol (2000) 278: C570-81 [PMID:10712246]; J Biol Chem (1997) 272: 32723-6 [PMID:9407042]; J Gen Physiol (1993) 102: 601-30 [PMID:7505804] |
KNa1.1 in Mouse [GtoPdb: 385] [UniProtKB: Q6ZPR4] | ||||||||
GtoPdb | - | - | 6.5 | pIC50 | - | - | - | J Gen Physiol (2006) 127: 205-15 [PMID:16446508] |
TRPC5 in Human [GtoPdb: 490] [UniProtKB: Q9UL62] | ||||||||
GtoPdb | - | - | 6.2 | pEC50 | 635 | nM | EC50 | |
TRPC5 in Mouse [GtoPdb: 490] [UniProtKB: Q9QX29] | ||||||||
GtoPdb | - | - | 6 | pEC50 | - | - | - |
J Gen Physiol (2009) 133: 525-46 [PMID:19398778]; J Biol Chem (2009) 284: 34423-32 [PMID:19815560] |
TRPM4 in Human [GtoPdb: 496] [UniProtKB: Q8TD43] | ||||||||
GtoPdb | - | - | 6.3 | pEC50 | 500 | nM | EC50 |
J Biol Chem (2005) 280: 6423-33 [PMID:15590641]; EMBO J (2006) 25: 467-78 [PMID:16424899]; Mol Pharmacol (2006) 69: 1413-20 [PMID:16407466]; J Physiol (Lond.) (2004) 560: 753-65 [PMID:15331675] |
TRPM5 in Mouse [GtoPdb: 497] [UniProtKB: Q9JJH7] | ||||||||
GtoPdb | - | - | 6.2 | pEC50 | 700 | nM | EC50 |
Cell Calcium (2005) 37: 267-78 [PMID:15670874]; Curr Biol (2003) 13: 1153-8 [PMID:12842017]; Proc Natl Acad Sci USA (2003) 100: 15160-5 [PMID:14657398] |
TRPM6 in Human [GtoPdb: 498] [UniProtKB: Q9BX84] | ||||||||
GtoPdb | - | - | 5.32 | pIC50 | 4800 | nM | IC50 | |
TRPP1 in Human [GtoPdb: 504] [UniProtKB: Q13563] | ||||||||
GtoPdb | - | - | 6 | pEC50 | - | - | - | Nat Cell Biol (2002) 4: 191-7 [PMID:11854751] |
ZAC in Human [GtoPdb: 587] [UniProtKB: Q401N2] | ||||||||
GtoPdb | - | - | 2.03 | pIC50 | - | - | - | Biochem Pharmacol (2016) 103: 109-17 [PMID:26872532] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.