ChEMBL ligand: CHEMBL1272 (A10BX02, AG-EE 623 ZW, AG-EE-623-ZW, AG-EE-623ZW, AGEE-623ZW, Enyglid, Novonorm, NSC-759893, Prandin, Repaglinida, Repaglinide, Repaglinide accord, Repaglinide component of prandimet, Repaglinide krka, Repaglinide teva)
ATP-binding cassette, sub-family C (CFTR/MRP), member 8/ATP-binding cassette sub-family C member 8 in Human [ChEMBL: CHEMBL2071] [GtoPdb: 2594] [UniProtKB: Q09428] There should be some charts here, you may need to enable JavaScript!
Organic cation transporter 1/Solute carrier family 22 member 1 in Human [ChEMBL: CHEMBL5685] [GtoPdb: 1019] [UniProtKB: O15245] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
ATP-binding cassette, sub-family C (CFTR/MRP), member 8/ATP-binding cassette sub-family C member 8 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2071] [GtoPdb: 2594] [UniProtKB: Q09428]
ChEMBL	Displacement of [3H]glibenclamide from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)	B	7.3	pKd	50	nM	Kd	Bioorg Med Chem Lett (2004) 14: 5205-5209 [PMID:15380228]
GtoPdb	-	-	6.97	pIC50	106	nM	IC50	Bioorg Med Chem Lett (2004) 14: 5205-9 [PMID:15380228]
ChEMBL	In vitro displacement of [3H]glibenclamide (IC50=0.61) from COS-1 cells expressing Sulfonylurea receptor 1 (SUR-1)	B	6.97	pIC50	106	nM	IC50	Bioorg Med Chem Lett (2004) 14: 5205-5209 [PMID:15380228]
Organic cation transporter 1/Solute carrier family 22 member 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5685] [GtoPdb: 1019] [UniProtKB: O15245]
ChEMBL	Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy	B	5.04	pIC50	9200	nM	IC50	J Med Chem (2008) 51: 5932-5942 [PMID:18788725]

ChEMBL data shown on this page come from version 36:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]