ChEMBL ligand: CHEMBL574003 (HQL-79)
H-PGDS/Hematopoietic prostaglandin D synthase in Human [ChEMBL: CHEMBL5879] [GtoPdb: 1381] [UniProtKB: O60760] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
H-PGDS/Hematopoietic prostaglandin D synthase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5879] [GtoPdb: 1381] [UniProtKB: O60760]
ChEMBL	Competitive inhibition of human HPGDS using PGH2 as substrate	B	5.3	pKi	5000	nM	Ki	Bioorg Med Chem Lett (2021) 34: 127759-127759 [PMID:33383152]
ChEMBL	Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay at 50 uM	B	4.13	pIC50	73900	nM	IC50	J Med Chem (2010) 53: 5536-5548 [PMID:20684598]
ChEMBL	Inhibition of human H-PGDS expressed in Escherichia coli BL21 DE2 by enzyme immuno assay	B	5.42	pIC50	3800	nM	IC50	J Med Chem (2010) 53: 5536-5548 [PMID:20684598]
GtoPdb	-	-	5.5	pIC50	-	-	-	J Biol Chem (2006) 281: 15277-86 [PMID:16547010]
ChEMBL	Inhibition of human H-PGDS expressed in Escherichia coli BL21 assessed as rate of glutathione-chloro-dinitro benzene conjugation	B	5.74	pIC50	1800	nM	IC50	Eur J Med Chem (2010) 45: 447-454 [PMID:19939518]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]