JMV1431 [Ligand Id: 656] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL408846 (JMV 1431) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| B1 receptor/Bradykinin B1 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4308] [GtoPdb: 41] [UniProtKB: P46663] | ||||||||
| ChEMBL | Ability to bind to human cloned B1 receptor in competition binding experiments with [3H][des-Arg10,Leu9]-Kallidin. | B | 7.08 | pKi | 83 | nM | Ki | J Med Chem (2000) 43: 2382-2386 [PMID:10882364] |
| GtoPdb | - | - | 7.1 | pKi | - | - | - | J Med Chem (2000) 43: 2382-6 [PMID:10882364] |
| B2 receptor/Bradykinin B2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3157] [GtoPdb: 42] [UniProtKB: P30411] | ||||||||
| ChEMBL | Ability to bind to human cloned B2 receptor in competition binding experiments with [3H]- bradykinin | B | 8.36 | pKi | 4.4 | nM | Ki | J Med Chem (2000) 43: 2382-2386 [PMID:10882364] |
| GtoPdb | - | - | 8.4 | pKi | - | - | - | J Med Chem (2000) 43: 2382-6 [PMID:10882364] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
