SF-11 [Ligand Id: 6404] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL548708 (TCMDC-124500)
  • TRPML3 in Human [GtoPdb: 503] [UniProtKB: Q8TDD5]
Created with Highcharts 10.3.3ValuesChart context menuTRPML3pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
TRPML3 in Human [GtoPdb: 503] [UniProtKB: Q8TDD5]
GtoPdb - - 6.59 pEC50 260 nM EC50 Chem Biol (2010) 17: 135-48 [PMID:20189104]

ChEMBL data shown on this page come from version 35:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]