ChEMBL ligand: CHEMBL430226
Aryl hydrocarbon receptor in Human [ChEMBL: CHEMBL3201] [GtoPdb: 2951] [UniProtKB: P35869] There should be some charts here, you may need to enable JavaScript!
cyclin dependent kinase 1/Cyclin-dependent kinase 1/cyclin B in Human [ChEMBL: CHEMBL2094127] [GtoPdb: 1961] [UniProtKB: O95067, P06493, P14635, Q8WWL7] There should be some charts here, you may need to enable JavaScript!
cyclin dependent kinase 5/Cyclin-dependent kinase 5/CDK5 activator 1 in Human [ChEMBL: CHEMBL1907600] [GtoPdb: 1977] [UniProtKB: Q00535, Q15078] There should be some charts here, you may need to enable JavaScript!
glycogen synthase kinase 3 alpha in Pig [GtoPdb: 2029] There should be some charts here, you may need to enable JavaScript!
glycogen synthase kinase 3 beta in Pig [GtoPdb: 2030] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Aryl hydrocarbon receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3201] [GtoPdb: 2951] [UniProtKB: P35869]
ChEMBL	Agonist activity at human aryl hydrocarbon receptor	F	6.8	pEC50	160	nM	EC50	Proc. Natl. Acad. Sci. U.S.A. (2007) 104: 20523-20528 [PMID:18077363]
cyclin dependent kinase 1/Cyclin-dependent kinase 1/cyclin B in Human (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL2094127] [GtoPdb: 1961] [UniProtKB: O95067, P06493, P14635, Q8WWL7]
ChEMBL	Inhibitory activity against cyclin dependent kinase 1-cyclinB from starfish (Marthasterias glacialis) oocytes	B	4.2	pIC50	63000	nM	IC50	J. Med. Chem. (2004) 47: 935-946 [PMID:14761195]
ChEMBL	Inhibition of CDK1/cyclinB	B	4.2	pIC50	63000	nM	IC50	Trends Pharmacol. Sci. (2004) 25: 471-480 [PMID:15559249]
cyclin dependent kinase 5/Cyclin-dependent kinase 5/CDK5 activator 1 in Human (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL1907600] [GtoPdb: 1977] [UniProtKB: Q00535, Q15078]
ChEMBL	Inhibitory activity against Cyclin-dependent kinase 5-p35nck5a	B	5.62	pIC50	2400	nM	IC50	J. Med. Chem. (2004) 47: 935-946 [PMID:14761195]
glycogen synthase kinase 3 alpha in Pig [GtoPdb: 2029]
GtoPdb	Measured using GSK3 as a complex of α and β isozymes, isolated from pig brain	-	8	pIC50	10	nM	IC50	J Med Chem (2004) 47: 935-46 [PMID:14761195]
glycogen synthase kinase 3 beta in Pig [GtoPdb: 2030]
GtoPdb	Measured using GSK3 as a complex of α and β isozymes, isolated from pig brain	-	8	pIC50	10	nM	IC50	J Med Chem (2004) 47: 935-46 [PMID:14761195]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]