Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
ChEMBL ligand: CHEMBL2178734 |
---|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
---|---|---|---|---|---|---|---|---|
cyclin dependent kinase 1 in Human [GtoPdb: 1961] [UniProtKB: P06493] | ||||||||
GtoPdb | CDK1/cyclin B complex | - | 6.49 | pIC50 | 320 | nM | IC50 |
J Med Chem (2004) 47: 935-46 [PMID:14761195]; Chem Biol (2003) 10: 1255-66 [PMID:14700633] |
cyclin dependent kinase 5 in Human [GtoPdb: 1977] [UniProtKB: Q00535] | ||||||||
GtoPdb | CDK5/p25 complex | - | 7.08 | pIC50 | 83 | nM | IC50 |
J Med Chem (2004) 47: 935-46 [PMID:14761195]; Chem Biol (2003) 10: 1255-66 [PMID:14700633] |
glycogen synthase kinase 3 alpha in Pig [GtoPdb: 2029] | ||||||||
GtoPdb | GSK3α/β complex from pig brain | - | 8.3 | pIC50 | 5 | nM | IC50 |
J Med Chem (2004) 47: 935-46 [PMID:14761195]; Chem Biol (2003) 10: 1255-66 [PMID:14700633] |
glycogen synthase kinase 3 beta in Pig [GtoPdb: 2030] | ||||||||
GtoPdb | GSK3α/β complex from pig brain | - | 8.3 | pIC50 | 5 | nM | IC50 |
J Med Chem (2004) 47: 935-46 [PMID:14761195]; Chem Biol (2003) 10: 1255-66 [PMID:14700633] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]