RO5166017 [Ligand Id: 5862] activity data from GtoPdb

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

  • TA1 receptor in Human [GtoPdb: 364] [UniProtKB: Q96RJ0]
  • TA1 receptor in Mouse [GtoPdb: 364] [UniProtKB: Q923Y8]
  • TA1 receptor in Rat [GtoPdb: 364] [UniProtKB: Q923Y9]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
TA1 receptor in Human [GtoPdb: 364] [UniProtKB: Q96RJ0]
GtoPdb - - 7.5 pKi 31 nM Ki Proc Natl Acad Sci USA (2011) 108: 8485-90 [PMID:21525407]
GtoPdb - - 7.3 pEC50 55 nM EC50 Proc Natl Acad Sci USA (2011) 108: 8485-90 [PMID:21525407]
TA1 receptor in Mouse [GtoPdb: 364] [UniProtKB: Q923Y8]
GtoPdb - - 8.7 pKi 1.9 nM Ki Proc Natl Acad Sci USA (2011) 108: 8485-90 [PMID:21525407]
GtoPdb - - 8.5 pEC50 3.3 nM EC50 Proc Natl Acad Sci USA (2011) 108: 8485-90 [PMID:21525407]
TA1 receptor in Rat [GtoPdb: 364] [UniProtKB: Q923Y9]
GtoPdb - - 8.6 pKi 2.7 nM Ki Proc Natl Acad Sci USA (2011) 108: 8485-90 [PMID:21525407]
GtoPdb - - 7.9 pEC50 14 nM EC50 Proc Natl Acad Sci USA (2011) 108: 8485-90 [PMID:21525407]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.