RPR121154 [Ligand Id: 580] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL368161
  • C5a1 receptor/C5a anaphylatoxin chemotactic receptor in Human [ChEMBL: CHEMBL2373] [GtoPdb: 32] [UniProtKB: P21730]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
C5a1 receptor/C5a anaphylatoxin chemotactic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2373] [GtoPdb: 32] [UniProtKB: P21730]
ChEMBL Compound was evaluated for the antagonistic activity against C5a anaphylatoxin chemotactic receptor in human neutrophil C5a stimulated respiratory burst assay F 6.1 pIC50 800 nM IC50 Bioorg. Med. Chem. Lett. (1997) 7: 907-912
GtoPdb - - 6.1 pIC50 - - - Bioorg Med Chem Lett (1997) 7: 907-912

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]