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ChEMBL ligand: CHEMBL178334 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Estrogen receptor-α/Estrogen receptor alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL206] [GtoPdb: 620] [UniProtKB: P03372] | ||||||||
ChEMBL | Inhibition of estrogen receptor alpha | B | 9.55 | pIC50 | 0.28 | nM | IC50 | Bioorg Med Chem Lett (2005) 15: 1505-1507 [PMID:15713417] |
ChEMBL | Displacement of [3H]-17beta-estradiol from ERalpha | B | 9.55 | pIC50 | 0.28 | nM | IC50 | Eur J Med Chem (2012) 51: 17-34 [PMID:22405286] |
Estrogen receptor-β/Estrogen receptor beta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL242] [GtoPdb: 621] [UniProtKB: Q92731] | ||||||||
ChEMBL | Inhibition of estrogen receptor beta | B | 7.47 | pIC50 | 33.92 | nM | IC50 | Bioorg Med Chem Lett (2005) 15: 1505-1507 [PMID:15713417] |
ChEMBL | Displacement of [3H]-17beta-estradiol from ERbeta | B | 7.47 | pIC50 | 33.92 | nM | IC50 | Eur J Med Chem (2012) 51: 17-34 [PMID:22405286] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]