ChEMBL ligand: CHEMBL460273 (JNJ-1661010)
Fatty acid amide hydrolase/Anandamide amidohydrolase in Human [ChEMBL: CHEMBL2243] [GtoPdb: 1400] [UniProtKB: O00519] Fatty acid amide hydrolase/Anandamide amidohydrolase in Rat [ChEMBL: CHEMBL3229] [GtoPdb: 1400] [UniProtKB: P97612] There should be some charts here, you may need to enable JavaScript!
Fatty acid amide hydrolase-2 in Human [GtoPdb: 1401] [UniProtKB: Q6GMR7] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Fatty acid amide hydrolase/Anandamide amidohydrolase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2243] [GtoPdb: 1400] [UniProtKB: O00519]
ChEMBL	Inhibition of human FAAH preincubated for 10 mins	B	7.15	pIC50	70	nM	IC50	Bioorg Med Chem Lett (2008) 18: 4838-4843 [PMID:18693015]
ChEMBL	Inhibition of human FAAH preincubated for 20 mins	B	7.48	pIC50	33	nM	IC50	Bioorg Med Chem Lett (2008) 18: 4838-4843 [PMID:18693015]
ChEMBL	Inhibition of FAAH	B	7.48	pIC50	33	nM	IC50	Bioorg Med Chem Lett (2009) 19: 4241-4244 [PMID:19515560]
ChEMBL	Inhibition of FAAH	B	7.48	pIC50	33	nM	IC50	Bioorg Med Chem Lett (2011) 21: 4674-4685 [PMID:21764305]
GtoPdb	-	-	7.8	pIC50	15.8	nM	IC50	Bioorg Med Chem Lett (2008) 18: 4838-43 [PMID:18693015]
ChEMBL	Inhibition of human FAAH preincubated for 40 mins	B	7.82	pIC50	15	nM	IC50	Bioorg Med Chem Lett (2008) 18: 4838-4843 [PMID:18693015]
ChEMBL	Inhibition of human FAAH after 60 mins	B	7.92	pIC50	12	nM	IC50	Bioorg Med Chem Lett (2008) 18: 4838-4843 [PMID:18693015]
ChEMBL	Apparent inhibition of human FAAH expressed in CHO-K1 cells using ethanolamine 1-3[H] as substrate after 30 mins by liquid scintillation counting	B	7.96	pIC50	11	nM	IC50	Bioorg Med Chem (2013) 21: 28-41 [PMID:23218778]
Fatty acid amide hydrolase/Anandamide amidohydrolase in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3229] [GtoPdb: 1400] [UniProtKB: P97612]
ChEMBL	Inhibition of rat FAAH preincubated for 20 mins	B	7.47	pIC50	34	nM	IC50	Bioorg Med Chem Lett (2008) 18: 4838-4843 [PMID:18693015]
ChEMBL	Inhibition of rat FAAH	B	7.47	pIC50	34	nM	IC50	Bioorg Med Chem Lett (2011) 21: 4674-4685 [PMID:21764305]
ChEMBL	Inhibition of rat FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarin	B	8	pIC50	10	nM	IC50	Bioorg Med Chem Lett (2011) 21: 2492-2496 [PMID:21392988]
Fatty acid amide hydrolase-2 in Human [GtoPdb: 1401] [UniProtKB: Q6GMR7]
GtoPdb	20 min preincubation	-	5.24	pIC50	5700	nM	IC50	Anesth Analg (2009) 108: 316-29 [PMID:19095868]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]