didanosine [Ligand Id: 4833] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1460 (BMY-40900, Ddi, Didanosina, (-)-didanosine, Didanosine, Didanosine system suitability mixture, Didanosinum, Dideoxyinosine (ddi), NSC-612049, Videx, Videx ec) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Human immunodeficiency virus type 1 reverse transcriptase in Human immunodeficiency virus 1 (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL247] [UniProtKB: Q72547] | ||||||||
| ChEMBL | Inhibitory concentration against SO561945 (HIV 1 mutant RT) viral infection of MT-4 cells | F | 5.15 | pIC50 | 7150 | nM | IC50 | Bioorg Med Chem Lett (2004) 14: 3173-3176 [PMID:15149669] |
| ChEMBL | Concentration required to protect the cell against HIV-1 strain IIIB viral cytopathogenicity by 50% in MT-4 cells | F | 5.27 | pIC50 | 5370 | nM | IC50 | Bioorg Med Chem Lett (2004) 14: 3173-3176 [PMID:15149669] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
