ChEMBL ligand: CHEMBL268697 (HC-3, hemicholinium-3)
Plasmodium falciparum [ChEMBL: CHEMBL364] There should be some charts here, you may need to enable JavaScript!
CHT in Human [GtoPdb: 914] [UniProtKB: Q9GZV3] There should be some charts here, you may need to enable JavaScript!
Choline transporter-like 1 in Human [GtoPdb: 1204] [UniProtKB: Q8WWI5] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Plasmodium falciparum (target type: ORGANISM) [ChEMBL: CHEMBL364]
ChEMBL	Antiplasmodial activity against Plasmodium falciparum Dd2 infected in human erythrocytes after 48 hrs by picogreen-microfluorimetric assay	F	4.3	pIC50	>50000	nM	IC50	Bioorg Med Chem Lett (2018) 28: 2485-2489 [PMID:29880399]
ChEMBL	Antiplasmodial activity against Plasmodium falciparum 3D7 infected in human erythrocytes after 72 hrs by SYBR green 1-based fluorimetric assay	F	4.3	pIC50	>50000	nM	IC50	Bioorg Med Chem Lett (2018) 28: 2485-2489 [PMID:29880399]
CHT in Human [GtoPdb: 914] [UniProtKB: Q9GZV3]
GtoPdb	-	-	8	pKi	10	nM	Ki	Neurochem Res (2003) 28: 483-8 [PMID:12675135]
Choline transporter-like 1 in Human [GtoPdb: 1204] [UniProtKB: Q8WWI5]
GtoPdb	-	-	4.5	pKi	31000	nM	Ki

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]