Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
ChEMBL ligand: CHEMBL268697 (HC-3, hemicholinium-3) |
---|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
---|---|---|---|---|---|---|---|---|
Plasmodium falciparum (target type: ORGANISM) [ChEMBL: CHEMBL364] | ||||||||
ChEMBL | Antiplasmodial activity against Plasmodium falciparum Dd2 infected in human erythrocytes after 48 hrs by picogreen-microfluorimetric assay | F | 4.3 | pIC50 | >50000 | nM | IC50 | Bioorg Med Chem Lett (2018) 28: 2485-2489 [PMID:29880399] |
ChEMBL | Antiplasmodial activity against Plasmodium falciparum 3D7 infected in human erythrocytes after 72 hrs by SYBR green 1-based fluorimetric assay | F | 4.3 | pIC50 | >50000 | nM | IC50 | Bioorg Med Chem Lett (2018) 28: 2485-2489 [PMID:29880399] |
CHT in Human [GtoPdb: 914] [UniProtKB: Q9GZV3] | ||||||||
GtoPdb | - | - | 8 | pKi | 10 | nM | Ki | Neurochem Res (2003) 28: 483-8 [PMID:12675135] |
Choline transporter-like 1 in Human [GtoPdb: 1204] [UniProtKB: Q8WWI5] | ||||||||
GtoPdb | - | - | 4.5 | pKi | 31000 | nM | Ki |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]