ChEMBL ligand: CHEMBL212579 (Benzamil)
ENaC α/Amiloride-sensitive sodium channel alpha-subunit in Human [ChEMBL: CHEMBL1791] [GtoPdb: 738] [UniProtKB: P37088] There should be some charts here, you may need to enable JavaScript!
TRPP2 in Human [GtoPdb: 505] [UniProtKB: Q9P0L9] There should be some charts here, you may need to enable JavaScript!
ASIC1 in Human [GtoPdb: 684] [UniProtKB: P78348] There should be some charts here, you may need to enable JavaScript!
ENaCαβγ in Human [GtoPdb: 742] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
ENaC α/Amiloride-sensitive sodium channel alpha-subunit in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1791] [GtoPdb: 738] [UniProtKB: P37088]
ChEMBL	Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assay	B	7.18	pIC50	66	nM	IC50	J Med Chem (2006) 49: 4098-4115 [PMID:16821771]
TRPP2 in Human [GtoPdb: 505] [UniProtKB: Q9P0L9]
GtoPdb	-	-	6	pIC50	1100	nM	IC50
ASIC1 in Human [GtoPdb: 684] [UniProtKB: P78348]
GtoPdb	-	-	5	pIC50	10000	nM	IC50	Nature (1997) 386: 173-7 [PMID:9062189]
ENaCαβγ in Human [GtoPdb: 742]
GtoPdb	-	-	8	pIC50	~10	nM	IC50

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]