R-spondin-3 [Ligand Id: 3699] activity data from GtoPdb

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  • LGR4 in Human [GtoPdb: 147] [UniProtKB: Q9BXB1]
Created with Highcharts 10.3.3ValuesChart context menuLGR4pKd HumanpKi HumanpIC50 HumanpEC50 Human024681012Highcharts.com
  • LGR5 in Human [GtoPdb: 148] [UniProtKB: O75473]
Created with Highcharts 10.3.3ValuesChart context menuLGR5pKd HumanpKi HumanpIC50 HumanpEC50 Human024681012Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
LGR4 in Human [GtoPdb: 147] [UniProtKB: Q9BXB1]
GtoPdb - - 8.66 pKd 2.2 nM Kd EMBO Rep (2011) 12: 1055-61 [PMID:21909076]
GtoPdb - - 10.7 pEC50 0.02 nM EC50 Proc Natl Acad Sci USA (2011) 108: 11452-7 [PMID:21693646]
LGR5 in Human [GtoPdb: 148] [UniProtKB: O75473]
GtoPdb - - 11 pEC50 0.01 nM EC50 Proc Natl Acad Sci USA (2011) 108: 11452-7 [PMID:21693646]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.