mitemcinal [Ligand Id: 3511] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1778156 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| motilin receptor/Motilin receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2203] [GtoPdb: 297] [UniProtKB: O43193] | ||||||||
| ChEMBL | Antagonist activity at MLNR (unknown origin) | B | 8.4 | pIC50 | 3.98 | nM | IC50 | J Med Chem (2013) 56: 1197-1210 [PMID:23281966] |
| motilin receptor in Rabbit [GtoPdb: 297] | ||||||||
| GtoPdb | - | - | 8.2 | pIC50 | - | - | - | Clin Exp Pharmacol Physiol (1999) 26: 242-5 [PMID:10081621] |
| GtoPdb | - | - | 7.8 | pEC50 | - | - | - |
Pharmacology (2007) 79: 137-48 [PMID:17183187]; Bioorg Med Chem Lett (1994) 4: 1347-1352 |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
