fluoxymesterone [Ligand Id: 2861] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1445 (Android-f, Androxy, Fluoximesterone, Fluoxymesterone, Fluoxymesterone ciii, Halotestin, NSC-10704, NSC-12165, Ora-testryl) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| Androgen receptor/Androgen Receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1871] [GtoPdb: 628] [UniProtKB: P10275] | ||||||||
| GtoPdb | - | - | 8.24 | pKi | 5.7 | nM | Ki | J Med Chem (2007) 50: 2486-96 [PMID:17439112] |
| ChEMBL | Displacement of [3H]DHT from human AR expressed in MDA-MB-453 cells | B | 8.24 | pKi | 5.7 | nM | Ki | J Med Chem (2007) 50: 2486-2496 [PMID:17439112] |
| ChEMBL | Antagonist activity at human androgen receptor expressed in CV1 cells by transcriptional activation assay | F | 5 | pIC50 | >10000 | nM | IC50 | J Med Chem (2007) 50: 2486-2496 [PMID:17439112] |
| ChEMBL | Agonist activity at human androgen receptor expressed in CV1 cells by transcriptional activation assay | F | 9.52 | pEC50 | 0.3 | nM | EC50 | J Med Chem (2007) 50: 2486-2496 [PMID:17439112] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
