dihydroergocryptine [Ligand Id: 282] activity data from GtoPdb

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  • 5-HT2B receptor in Human [GtoPdb: 7] [UniProtKB: P41595]
  • This target only has 1 pki data point
  • 7.48
1 _lig_chart_1 5-HT2B receptor Human
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  • 5-HT7 receptor in Mouse [GtoPdb: 12] [UniProtKB: P32304]
  • 5-HT7 receptor in Rat [GtoPdb: 12] [UniProtKB: P32305]
  • 6.5
2 _lig_chart_2 5-HT7 receptor MouseRat
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
5-HT2B receptor in Human [GtoPdb: 7] [UniProtKB: P41595]
GtoPdb Biased for β-arrestin signalling. - 7.48 pKi - - - Science (2013) 340: 615-9 [PMID:23519215]
5-HT7 receptor in Mouse [GtoPdb: 12] [UniProtKB: P32304]
GtoPdb - - 7 pKi - - - Mol Pharmacol (1993) 44: 229-36 [PMID:8394987]
5-HT7 receptor in Rat [GtoPdb: 12] [UniProtKB: P32305]
GtoPdb - - 6.5 pKi - - - Proc Natl Acad Sci USA (1993) 90: 8547-51 [PMID:8397408]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.