ChEMBL ligand: CHEMBL2386188
TRPV6/Transient receptor potential cation channel subfamily V member 6 in Human [ChEMBL: CHEMBL1628465] [GtoPdb: 512] [UniProtKB: Q9H1D0] There should be some charts here, you may need to enable JavaScript!
TRPV3 in Mouse [GtoPdb: 509] [UniProtKB: Q8K424] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
TRPV6/Transient receptor potential cation channel subfamily V member 6 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1628465] [GtoPdb: 512] [UniProtKB: Q9H1D0]
ChEMBL	Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Ca2+ influx after 5 mins by FLIPR assay	B	4.72	pIC50	19200	nM	IC50	Bioorg Med Chem (2013) 21: 3202-3213 [PMID:23602525]
ChEMBL	Inhibition of human TRPV6 transfected in HEK293 cells assessed as inhibition of Cd2+ influx after 5 mins by FLIPR assay	B	4.75	pIC50	17700	nM	IC50	Bioorg Med Chem (2013) 21: 3202-3213 [PMID:23602525]
TRPV3 in Mouse [GtoPdb: 509] [UniProtKB: Q8K424]
GtoPdb	Patch clamp electrophysiology	-	4.2	pEC50	63095	nM	EC50	J Biol Chem (2005) 280: 15928-41 [PMID:15722340]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]