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ChEMBL ligand: CHEMBL448741 (Dihydrospingosine, DL-erythro-Dihydrosphingosine) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Cholesteryl ester transfer protein in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3572] [UniProtKB: P11597] | ||||||||
ChEMBL | Compound was measured for its inhibitory activity against cholesteryl ester transfer protein (CETP) | B | 4.89 | pIC50 | 12900 | nM | IC50 | Bioorg. Med. Chem. Lett. (1997) 7: 1481-1482 |
Plasmodium falciparum (target type: ORGANISM) [ChEMBL: CHEMBL364] | ||||||||
ChEMBL | Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay | F | 4.9 | pIC50 | 12589.25 | nM | IC50 | Nat. Chem. Biol. (2009) 5: 765-771 [PMID:19734910] |
ChEMBL | Antiplasmodial activity against Plasmodium falciparum D10 after 72 hrs by SYBR green assay | F | 4.9 | pIC50 | 12589.25 | nM | IC50 | Nat. Chem. Biol. (2009) 5: 765-771 [PMID:19734910] |
ChEMBL | Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay | F | 5 | pIC50 | 10000 | nM | IC50 | Nat. Chem. Biol. (2009) 5: 765-771 [PMID:19734910] |
TRPM3 in Human [GtoPdb: 495] [UniProtKB: Q9HCF6] | ||||||||
GtoPdb | - | - | 4.7 | pEC50 | - | - | - | Mol Pharmacol (2005) 67: 798-805 [PMID:15550678] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]