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ChEMBL ligand: CHEMBL86 (Clopra, Clopra-"Yellow", Elieten, Maxolon, Methoxyclopramide, Metoclopramide, Reglan, Terperan) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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acetylcholinesterase (Yt blood group)/Acetylcholinesterase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL220] [GtoPdb: 2465] [UniProtKB: P22303] | ||||||||
ChEMBL | Inhibition of guinea pig acetylcholinesterase | B | 4.7 | pIC50 | >20000 | nM | IC50 | J Med Chem (1993) 36: 572-579 [PMID:8496937] |
Alpha-1a adrenergic receptor in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4892] [UniProtKB: P18130] | ||||||||
ChEMBL | Binding affinity was evaluated by Alpha-1 adrenergic receptor in calf cortex by displacing prazosin | B | 5 | pKd | <5 | - | pKD | J Med Chem (1995) 38: 2326-2330 [PMID:7608898] |
α2A-adrenoceptor/Alpha-2a adrenergic receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1867] [GtoPdb: 25] [UniProtKB: P08913] | ||||||||
ChEMBL | DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912) | B | 5.99 | pKi | 1020 | nM | Ki | DrugMatrix in vitro pharmacology data |
ChEMBL | DRUGMATRIX: Alpha-2A adrenergic receptor radioligand binding (ligand: MK-912) | B | 5.57 | pIC50 | 2721 | nM | IC50 | DrugMatrix in vitro pharmacology data |
CYP2D6/Cytochrome P450 2D6 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL289] [GtoPdb: 1329] [UniProtKB: P10635] | ||||||||
ChEMBL | DRUGMATRIX: CYP450, 2D6 enzyme inhibition (substrate: 3-Cyano-7-ethoxycoumarin) | B | 6.1 | pIC50 | 800 | nM | IC50 | DrugMatrix in vitro pharmacology data |
Dopamine D1 receptor in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2967] [UniProtKB: Q95136] | ||||||||
ChEMBL | Binding affinity was evaluated by Dopamine receptor D1 agonism in the calf striatum by displacing SCH 23390 | B | 5 | pKd | <5 | - | pKD | J Med Chem (1995) 38: 2326-2330 [PMID:7608898] |
D2 receptor/Dopamine D2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL217] [GtoPdb: 215] [UniProtKB: P14416] | ||||||||
ChEMBL | Radioligand Binding Assay: The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a functional antagonist assay. For the radioligand binding assay, cell membranes of dopamine D2 receptor expressing cells were incubated with [3H]spiperone and competing drugs in buffer. The assay was terminated by rapid filtration, and the bound radioactive signal was determined by liquid scintillation counting. | B | 7.19 | pKi | 64 | nM | Ki | US-9132134-B2. Methods for treating GI tract disorders (2015) |
ChEMBL | DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone) | B | 7.38 | pKi | 42 | nM | Ki | DrugMatrix in vitro pharmacology data |
ChEMBL | DRUGMATRIX: Dopamine D2L radioligand binding (ligand: [3H] Spiperone) | B | 6.9 | pIC50 | 127 | nM | IC50 | DrugMatrix in vitro pharmacology data |
Dopamine D2 receptor in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3998] [UniProtKB: P20288] | ||||||||
ChEMBL | Binding affinity was evaluated by Dopamine receptor D2 agonism in the calf striatum by displacing spiperone | B | 7.1 | pKd | 7.1 | - | pKD | J Med Chem (1995) 38: 2326-2330 [PMID:7608898] |
ChEMBL | Compound was evaluated for the binding affinity at Dopamine receptor D2 | B | 7.1 | pKi | 80 | nM | Ki | J Med Chem (1995) 38: 2326-2330 [PMID:7608898] |
D2 receptor in Mouse [GtoPdb: 215] [UniProtKB: P61168] | ||||||||
GtoPdb | - | - | 7.54 | pKi | 28.8 | nM | Ki | J Pharmacol Exp Ther (1998) 287: 725-32 [PMID:9808703] |
D2 receptor/Dopamine D2 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL339] [GtoPdb: 215] [UniProtKB: P61169] | ||||||||
ChEMBL | Affinity towards Dopamine receptor D2 in rat striatum using [3H]spiperone as radioligand | B | 6.52 | pKi | 303 | nM | Ki | J Med Chem (2003) 46: 702-715 [PMID:12593651] |
ChEMBL | Binding affinity against Dopamine receptor D2 using [3H]spiperone as radioligand in rat striatum | B | 6.55 | pKi | 285 | nM | Ki | Bioorg Med Chem Lett (1995) 5: 795-798 |
ChEMBL | Compound was evaluated for binding affinity towards DA D-2 receptor using radioligand [3H]SPI | B | 6.63 | pKi | 235 | nM | Ki | J Med Chem (1992) 35: 2355-2363 [PMID:1535660] |
ChEMBL | Binding affinity to dopamine receptor D2 | B | 6.95 | pKi | 113 | nM | Ki | J Med Chem (1992) 35: 1486-1489 [PMID:1573641] |
ChEMBL | Compound was evaluated for binding affinity towards DA D-2 receptor using radioligand [3H]SPI | B | 6.98 | pKi | 104 | nM | Ki | J Med Chem (1992) 35: 2355-2363 [PMID:1535660] |
ChEMBL | Inhibitory concentration required for displacing radioligand [3H]SPI from DA D-2 receptor | B | 6.09 | pIC50 | 820 | nM | IC50 | J Med Chem (1992) 35: 2355-2363 [PMID:1535660] |
ChEMBL | Inhibitory activity against dopamine receptor D2 by 3H ligand binding experiments. | B | 6.2 | pIC50 | 630 | nM | IC50 | J Med Chem (1991) 34: 616-624 [PMID:1995885] |
ChEMBL | In vitro antagonistic activity against Dopamine receptor D2 was evaluated for the inhibition of [3H]spiperone binding | B | 6.25 | pIC50 | 565 | nM | IC50 | J Med Chem (1988) 31: 1548-1558 [PMID:3397992] |
ChEMBL | Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligand | B | 6.32 | pIC50 | 480 | nM | IC50 | Bioorg Med Chem Lett (1998) 8: 619-624 [PMID:9871571] |
ChEMBL | Inhibition of [3H]- spiperone binding to rat brain Dopamine receptor D2 | B | 6.32 | pIC50 | 480 | nM | IC50 | Bioorg Med Chem Lett (1998) 8: 1551-1554 [PMID:9873388] |
ChEMBL | Concentration of compound required to inhibit the binding of radioligand [3H]spiperone to Dopamine receptor D2 in rat brain synaptic membrane | B | 6.35 | pIC50 | 444 | nM | IC50 | J Med Chem (2003) 46: 702-715 [PMID:12593651] |
D3 receptor/Dopamine D3 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL234] [GtoPdb: 216] [UniProtKB: P35462] | ||||||||
ChEMBL | DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone) | B | 7.17 | pKi | 68 | nM | Ki | DrugMatrix in vitro pharmacology data |
ChEMBL | Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cells | B | 7.57 | pKi | 27 | nM | Ki | J Med Chem (2003) 46: 4377-4392 [PMID:14521403] |
ChEMBL | Radioligand Binding Assay: The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a functional antagonist assay. For the radioligand binding assay, cell membranes of dopamine D2 receptor expressing cells were incubated with [3H]spiperone and competing drugs in buffer. The assay was terminated by rapid filtration, and the bound radioactive signal was determined by liquid scintillation counting. | B | 7.8 | pKi | 16 | nM | Ki | US-9132134-B2. Methods for treating GI tract disorders (2015) |
ChEMBL | DRUGMATRIX: Dopamine D3 radioligand binding (ligand: [3H] Spiperone) | B | 6.7 | pIC50 | 200 | nM | IC50 | DrugMatrix in vitro pharmacology data |
D3 receptor/Dopamine D3 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3138] [GtoPdb: 216] [UniProtKB: P19020] | ||||||||
ChEMBL | Concentration of compound required to inhibit the binding of radioligand [3H](R)-7-OH-DPAT to Dopamine receptor D3 in rat striatum | B | 7.21 | pIC50 | 61.3 | nM | IC50 | J Med Chem (2003) 46: 702-715 [PMID:12593651] |
Lactoperoxidase in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2295561] [UniProtKB: P80025] | ||||||||
ChEMBL | Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 mins | B | 5.3 | pIC50 | >5000 | nM | IC50 | J Med Chem (2017) 60: 6563-6586 [PMID:28671460] |
myeloperoxidase/Myeloperoxidase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2439] [GtoPdb: 2789] [UniProtKB: P05164] | ||||||||
ChEMBL | Inhibition of recombinant MPO (unknown origin) assessed as reduction in LDL oxidation in presence of H2O2 and HCl after 5 mins by ELISA | B | 5.3 | pIC50 | >5000 | nM | IC50 | J Med Chem (2017) 60: 6563-6586 [PMID:28671460] |
ChEMBL | Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed by H2O2 addition measured after 5 mins | B | 6.46 | pIC50 | 350 | nM | IC50 | J Med Chem (2017) 60: 6563-6586 [PMID:28671460] |
5-HT1A receptor/Serotonin 1a (5-HT1a) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL214] [GtoPdb: 1] [UniProtKB: P08908] | ||||||||
ChEMBL | Binding affinity was evaluated by 5-hydroxytryptamine 1A receptor agonism in the pig cortex by displacing 8-OH-DPAT | B | 5.1 | pKd | 5.1 | - | pKD | J Med Chem (1995) 38: 2326-2330 [PMID:7608898] |
5-HT2A receptor/Serotonin 2a (5-HT2a) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL224] [GtoPdb: 6] [UniProtKB: P28223] | ||||||||
ChEMBL | DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin) | B | 5.98 | pKi | 1050 | nM | Ki | DrugMatrix in vitro pharmacology data |
ChEMBL | DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2A radioligand binding (ligand: [3H] Ketanserin) | B | 5.43 | pIC50 | 3675 | nM | IC50 | DrugMatrix in vitro pharmacology data |
5-HT2A receptor/Serotonin 2a (5-HT2a) receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL322] [GtoPdb: 6] [UniProtKB: P14842] | ||||||||
ChEMBL | Binding affinity was evaluated by 5-hydroxytryptamine 2A receptor agonism in the rat cortex by displacing ketanserin | B | 5.4 | pKd | 5.4 | - | pKD | J Med Chem (1995) 38: 2326-2330 [PMID:7608898] |
5-HT2B receptor/Serotonin 2b (5-HT2b) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1833] [GtoPdb: 7] [UniProtKB: P41595] | ||||||||
ChEMBL | DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide) | B | 6.4 | pKi | 401 | nM | Ki | DrugMatrix in vitro pharmacology data |
ChEMBL | DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2B radioligand binding (ligand: [3H] Lysergic acid diethylamide) | B | 6.2 | pIC50 | 630 | nM | IC50 | DrugMatrix in vitro pharmacology data |
5-HT2C receptor/Serotonin 2c (5-HT2c) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL225] [GtoPdb: 8] [UniProtKB: P28335] | ||||||||
ChEMBL | DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine) | B | 5.9 | pKi | 1248 | nM | Ki | DrugMatrix in vitro pharmacology data |
ChEMBL | DRUGMATRIX: Serotonin (5-Hydroxytryptamine) 5-HT2C radioligand binding (ligand: [3H] Mesulergine) | B | 5.62 | pIC50 | 2383 | nM | IC50 | DrugMatrix in vitro pharmacology data |
5-HT3E/5-HT3B/5-HT3A/5-HT3D/5-HT3C/Serotonin 3 (5-HT3) receptor in Human (target type: PROTEIN COMPLEX GROUP) [ChEMBL: CHEMBL2094132] [GtoPdb: 377, 374, 373, 376, 375] [UniProtKB: A5X5Y0, O95264, P46098, Q70Z44, Q8WXA8] | ||||||||
ChEMBL | Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor of isolated guinea pig ileum (GPI) | F | 5.2 | pKd | 6309.57 | nM | Kd | Bioorg Med Chem Lett (1992) 2: 461-466 |
ChEMBL | Evaluated for the antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor in isolated perfused rabbit heart (RH) | F | 7.1 | pKd | 79.43 | nM | Kd | Bioorg Med Chem Lett (1992) 2: 461-466 |
ChEMBL | Potency at neuronal 5-hydroxytryptamine 3 receptors in the rabbit heart | B | 7.3 | pKd | 50.12 | nM | Kd | J Med Chem (1990) 33: 1594-1600 [PMID:2342053] |
ChEMBL | Antagonistic activity against Serotonin 5-hydroxytryptamine 3 receptor in isolated rabbit vagus nerve (RVN) | F | 7.3 | pKd | 50.12 | nM | Kd | Bioorg Med Chem Lett (1992) 2: 461-466 |
5-HT3A/5-HT3B/Serotonin 3 (5-HT3) receptor in Rat (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL2094116] [GtoPdb: 373, 374] [UniProtKB: P35563, Q9JJ16] | ||||||||
ChEMBL | Displacement of the 5-hydroxytryptamine 3 receptor ligand [3H]GR-65630 from rat brain cortical membranes. | B | 6 | pKi | 995 | nM | Ki | J Med Chem (1992) 35: 895-903 [PMID:1312602] |
ChEMBL | Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide as a radioligand | B | 6.3 | pKi | 502 | nM | Ki | J Med Chem (1990) 33: 3176-3181 [PMID:2258903] |
ChEMBL | pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptor | B | 6.3 | pKi | 501.19 | nM | Ki | J Med Chem (1990) 33: 3176-3181 [PMID:2258903] |
ChEMBL | Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement. | B | 6.31 | pKi | 490 | nM | Ki | Bioorg Med Chem Lett (1996) 6: 263-266 |
ChEMBL | Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]BRL-43694 as radioligand in rat posterior cortex | B | 6.35 | pKi | 443 | nM | Ki | Bioorg Med Chem Lett (1995) 5: 795-798 |
ChEMBL | Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]BRL-43694 in rat posterior cortex | B | 6.35 | pKi | 443 | nM | Ki | Bioorg Med Chem Lett (1994) 4: 1433-1436 |
ChEMBL | Compound was evaluated for its binding affinity for 5-hydroxytryptamine 3 receptor by measuring displacement [3H]GR-65630 in rat cerebral cortex | B | 6.46 | pKi | 348 | nM | Ki | J Med Chem (1998) 41: 311-317 [PMID:9464362] |
ChEMBL | Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor | B | 6.62 | pKi | 240 | nM | Ki | J Med Chem (1992) 35: 1486-1489 [PMID:1573641] |
ChEMBL | Binding affinity to 5-hydroxytryptamine 3 receptor using [3H]quipazine as radioligand in rat cortex | B | 6.64 | pKi | 229.09 | nM | Ki | J Med Chem (1990) 33: 1594-1600 [PMID:2342053] |
ChEMBL | Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 5-hydroxytryptamine 3 receptor | B | 6.68 | pKi | 210 | nM | Ki | J Med Chem (2003) 46: 702-715 [PMID:12593651] |
ChEMBL | Binding affinity to 5-hydroxytryptamine 3 receptor using [3H]GR-65630 as radioligand in rat cortex | B | 6.7 | pKi | 199.53 | nM | Ki | J Med Chem (1990) 33: 1594-1600 [PMID:2342053] |
ChEMBL | Tested for its binding affinity by measuring its ability to displace [3H]granisetron from 5-hydroxytryptamine 3 receptor in rat cortex | B | 6.8 | pKi | 158.49 | nM | Ki | Bioorg Med Chem Lett (1993) 3: 633-634 |
ChEMBL | Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligand | B | 6.06 | pIC50 | 880 | nM | IC50 | Bioorg Med Chem Lett (1998) 8: 619-624 [PMID:9871571] |
ChEMBL | Inhibition of [3H]GR-65630 binding to rat cortical membrane 5-hydroxytryptamine 3 receptor | B | 6.06 | pIC50 | 880 | nM | IC50 | Bioorg Med Chem Lett (1998) 8: 1551-1554 [PMID:9873388] |
ChEMBL | Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain cortical membrane | B | 6.64 | pIC50 | 228 | nM | IC50 | J Med Chem (2003) 46: 702-715 [PMID:12593651] |
5-HT4 receptor/Serotonin 4 (5-HT4) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1875] [GtoPdb: 9] [UniProtKB: Q13639] | ||||||||
ChEMBL | Agonist activity against 5-HT4 receptor in rat esophageal muscularis mucosae | F | 6.1 | pEC50 | 794.33 | nM | EC50 | Bioorg Med Chem Lett (1994) 4: 2477-2480 |
5-HT4 receptor in Mouse [GtoPdb: 9] [UniProtKB: P97288] | ||||||||
GtoPdb | - | - | 6 | pKi | - | - | - | FEBS Lett (1996) 398: 19-25 [PMID:8946946] |
5-HT4 receptor/Serotonin 4 (5-HT4) receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4317] [GtoPdb: 9] [UniProtKB: Q62758] | ||||||||
ChEMBL | Binding affinity towards 5-hydroxytryptamine 4 receptor was determined in rat striatal membranes using [3H]GR-113808 as radioligand | B | 6 | pKi | >1000 | nM | Ki | J Med Chem (1997) 40: 608-621 [PMID:9046352] |
ChEMBL | Binding affinity against 5-hydroxytryptamine 4 receptor using [3H]GR-113808 as radioligand in rat striatum | B | 6.01 | pKi | 975 | nM | Ki | Bioorg Med Chem Lett (1994) 4: 1433-1436 |
ChEMBL | Binding affinity against 5-hydroxytryptamine 4 receptor using [3H]GR-113808 as radioligand in rat striatum | B | 6.01 | pKi | 974 | nM | Ki | Bioorg Med Chem Lett (1995) 5: 795-798 |
ChEMBL | Binding affinity at 5-hydroxytryptamine 4 receptor in rat striatum by [3H]GR-113808 displacement. | B | 6.05 | pKi | 900 | nM | Ki | Bioorg Med Chem Lett (1996) 6: 263-266 |
ChEMBL | In vitro relaxation of carbachol pre-contracted rat oesophageal TMM. | F | 5.72 | pEC50 | 1920 | nM | EC50 | Bioorg Med Chem Lett (1996) 6: 263-266 |
ChEMBL | Tested for its agonist potency against the 5-hydroxytryptamine 4 receptor located in the rat esophageal tunica muscularis mucosae | F | 6.1 | pEC50 | 794.33 | nM | EC50 | Bioorg Med Chem Lett (1993) 3: 633-634 |
Serotonin 4 (5-HT4) receptor in Guinea pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5017] [UniProtKB: O70528] | ||||||||
ChEMBL | Inhibition of [3H]GR-113808 binding to guinea pig striatum 5-hydroxytryptamine 4 receptor | B | 6.26 | pKi | 546 | nM | Ki | J Med Chem (2003) 46: 702-715 [PMID:12593651] |
ChEMBL | Concentration of compound required to inhibit the binding of radioligand [3H]GR-113808 to serotonin 5-hydroxytryptamine 4 receptor in guinea-pig striatum | B | 6.04 | pIC50 | 912 | nM | IC50 | J Med Chem (2003) 46: 702-715 [PMID:12593651] |
ChEMBL | 5-hydroxytryptamine 4 receptor agonist activity, concentration which gave 50% increase in the response to electrically-stimulated myenteric plexus and longitudinal muscle of the guinea pig ileum | F | 8.24 | pEC50 | 5.7 | nM | EC50 | J Med Chem (1997) 40: 608-621 [PMID:9046352] |
Organic cation transporter 1/Solute carrier family 22 member 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5685] [GtoPdb: 1019] [UniProtKB: O15245] | ||||||||
ChEMBL | Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy | B | 4.02 | pIC50 | 94800 | nM | IC50 | J Med Chem (2008) 51: 5932-5942 [PMID:18788725] |
5-HT3AB in Human [GtoPdb: 378] | ||||||||
GtoPdb | - | - | 5.7 | pKi | - | - | - | Neuropharmacology (2001) 41: 282-4 [PMID:11489465] |
5-HT3A in Human [GtoPdb: 379] | ||||||||
GtoPdb | - | - | 6.45 | pKi | 354 | nM | Ki |
Neuropharmacology (2001) 41: 282-4 [PMID:11489465]; Br J Pharmacol (1996) 118: 1237-45 [PMID:8818349] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]