spermidine [Ligand Id: 2390] activity data from GtoPdb and ChEMBL
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
| ChEMBL ligand: CHEMBL19612 (Spermidine) |
|---|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Carbonic anhydrase 15 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5973] [UniProtKB: Q99N23] | ||||||||
| ChEMBL | Inhibition of mouse carbonic anhydrase 15 by stopped flow CO2 hydration method | B | 5 | pKi | 10000 | nM | Ki | J Med Chem (2010) 53: 5511-5522 [PMID:20590092] |
| carbonic anhydrase 1/Carbonic anhydrase I in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL261] [GtoPdb: 2597] [UniProtKB: P00915] | ||||||||
| ChEMBL | Inhibition of human carbonic anhydrase 1 by stopped flow CO2 hydration method | B | 5.85 | pKi | 1400 | nM | Ki | J Med Chem (2010) 53: 5511-5522 [PMID:20590092] |
| carbonic anhydrase 2/Carbonic anhydrase II in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL205] [GtoPdb: 3092] [UniProtKB: P00918] | ||||||||
| ChEMBL | Inhibition of human carbonic anhydrase 2 by stopped flow CO2 hydration method | B | 5.95 | pKi | 1110 | nM | Ki | J Med Chem (2010) 53: 5511-5522 [PMID:20590092] |
| Carbonic anhydrase III in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2885] [UniProtKB: P07451] | ||||||||
| ChEMBL | Inhibition of human carbonic anhydrase 3 by stopped flow CO2 hydration method | B | 4.94 | pKi | 11500 | nM | Ki | J Med Chem (2010) 53: 5511-5522 [PMID:20590092] |
| carbonic anhydrase 4/Carbonic anhydrase IV in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3729] [GtoPdb: 2599] [UniProtKB: P22748] | ||||||||
| ChEMBL | Inhibition of human carbonic anhydrase 4 by stopped flow CO2 hydration method | B | 6.95 | pKi | 112 | nM | Ki | J Med Chem (2010) 53: 5511-5522 [PMID:20590092] |
| carbonic anhydrase 9/Carbonic anhydrase IX in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3594] [GtoPdb: 3055] [UniProtKB: Q16790] | ||||||||
| ChEMBL | Inhibition of human carbonic anhydrase 9 by stopped flow CO2 hydration method | B | 5.86 | pKi | 1370 | nM | Ki | J Med Chem (2010) 53: 5511-5522 [PMID:20590092] |
| carbonic anhydrase 5A/Carbonic anhydrase VA in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4789] [GtoPdb: 3093] [UniProtKB: P35218] | ||||||||
| ChEMBL | Inhibition of human carbonic anhydrase 5A by stopped flow CO2 hydration method | B | 5.91 | pKi | 1220 | nM | Ki | J Med Chem (2010) 53: 5511-5522 [PMID:20590092] |
| Carbonic anhydrase VB in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3969] [UniProtKB: Q9Y2D0] | ||||||||
| ChEMBL | Inhibition of human carbonic anhydrase 5B by stopped flow CO2 hydration method | B | 5.84 | pKi | 1440 | nM | Ki | J Med Chem (2010) 53: 5511-5522 [PMID:20590092] |
| Carbonic anhydrase VI in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3025] [UniProtKB: P23280] | ||||||||
| ChEMBL | Inhibition of human carbonic anhydrase 6 by stopped flow CO2 hydration method | B | 5.85 | pKi | 1410 | nM | Ki | J Med Chem (2010) 53: 5511-5522 [PMID:20590092] |
| carbonic anhydrase 7/Carbonic anhydrase VII in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2326] [GtoPdb: 2749] [UniProtKB: P43166] | ||||||||
| ChEMBL | Inhibition of human carbonic anhydrase 7 by stopped flow CO2 hydration method | B | 5.91 | pKi | 1230 | nM | Ki | J Med Chem (2010) 53: 5511-5522 [PMID:20590092] |
| carbonic anhydrase 12/Carbonic anhydrase XII in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3242] [GtoPdb: 2747] [UniProtKB: O43570] | ||||||||
| ChEMBL | Inhibition of human carbonic anhydrase 12 by stopped flow CO2 hydration method | B | 4.36 | pKi | 44100 | nM | Ki | J Med Chem (2010) 53: 5511-5522 [PMID:20590092] |
| carbonic anhydrase 13/Carbonic anhydrase XIII in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2186] [GtoPdb: 2748] [UniProtKB: Q9D6N1] | ||||||||
| ChEMBL | Inhibition of mouse carbonic anhydrase 13 by stopped flow CO2 hydration method | B | 4.94 | pKi | 11600 | nM | Ki | J Med Chem (2010) 53: 5511-5522 [PMID:20590092] |
| carbonic anhydrase 14/Carbonic anhydrase XIV in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3510] [GtoPdb: 2598] [UniProtKB: Q9ULX7] | ||||||||
| ChEMBL | Inhibition of human carbonic anhydrase 14 by stopped flow CO2 hydration method | B | 6 | pKi | 1000 | nM | Ki | J Med Chem (2010) 53: 5511-5522 [PMID:20590092] |
| Kir2.1 in Mouse [GtoPdb: 430] [UniProtKB: P35561] | ||||||||
| GtoPdb | - | - | 8.1 | pKd | - | - | - | Neuron (1995) 14: 1047-54 [PMID:7748552] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
